A new ascothoracidan species has been discovered off Taiwan in the north part of the west Pacific at SCUBA depths. Twelve specimens including both sexes of the new species, described herein as , were collected from colonies of the antipatharian Myriopathes cf. japonica Brook, 1889.
View Article and Find Full Text PDFA new ascothoracidan species, Gorgonolaureus bicornutus sp. nov., has been discovered off south-eastern Taiwan at a depth of 227 m.
View Article and Find Full Text PDFThree new 5-arylethynyl-2'-deoxyuridines containing bulky aryls have been prepared and tested against HSV-1 in Vero cells. The introduction of a substituent in the phenyl group of an inactive compound, 5-phenylethynyl-2'-deoxyuridine, leads to the appearance of anti-HSV properties. The most active compounds are those containing a polycyclic aromatic hydrocarbon residue attached to the 5 position of 2'-deoxyuridine through a rigid triple bond.
View Article and Find Full Text PDFA series of new 5-alkynyl-2'-deoxyuridines have been synthesized and their antiherpetic activity was tested in the cultured Vero cells on a model of herpes simplex virus type 1, including its acyclovir-resistant strains. Some test compounds were found to have a significant specific antiherpetic activity. Nucleoside XIV showed the greatest activity.
View Article and Find Full Text PDFNucleosides Nucleotides Nucleic Acids
December 2005
Eight 5-alkynyl-2'deoxyuridines containing different bulky substituents have been prepared and tested against HSV-1 in Vero cells. The compounds show positive antiviral activity. There is no obvious correlation between activity and substituent size.
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