[Microfocus radioimaging in the evaluation of bone regeneration in patients with congenital fissures of the alveolar process].

Congenital fissures of the alveolar process and hard palate are one of the severest pathologies of the teeth and jaws. Plain magnification microfocus radiography and microfocus radioimaging of the upper jaw with bite occlusion are the radiodiagnostic methods of choice for the evaluation of bone defects and regenerative processes. To study the regenerative processes, 52 patients aged 10-16 years with congenital fissures of the alveolar process and hard palate were examined after bone reparative surgery.

[Cone-beam tomography of congenital fissures of the alveolar process and palate].

Cone-beam tomography is one of the current radiodiagnostic techniques, which allows patients with congenital fissures of the alveolar process and soft and hard palates to be examined, by minimizing the radiation load. On surgical treatment planning, cone-beam tomography makes it possible to estimate the extent of a bone defect in the alveolar process, its sizes, the presence or absence of oronasal fistulas, the position of the intermaxilla, the state of bone tissue (sizes, density characteristics) in the genial area for an autograft, the degree of a maxillofacial deformity, and occlusive features. Postoperative cone-beam tomography permits one to estimate the degree of alveolar process recovery, the sizes of a regenerate, the processes of osteointegration, and the state of fixing elements and the donor bed.

[Digital volume tomography in the diagnosis of the surgical anatomy of the frontal recess area].

Frontal recess anatomy can be very complex, with accessory cells, such as frontal bulla, agger nasi, suprabulla, and frontal ethmoidal (Kuhn) cells, which may lead to obstruction of the frontal sinus. Digital volume tomography of paranasal sinuses used in this investigation revealed the rate of types of development of various anatomic structures and their correlation with frontal sinusitis in patients with (a study) and without the latter (a control group).

[Capacities of dental volume tomography of congenital clefts of the alveolar process and hard palatea].

Objective: to study the capacities of dental volume tomography in the examination of patients with congenital clefts of the alveolar process and hard palate. Subjects and methods. Thirty-five patients with congenital clefts of the alveolar process and hard palate were examined on a dental volume tomograph, an I-CAT cone X-ray beam scanner.

[The gentic principles for the design of live Salmonella vaccines].

The presently known methods of obtaining Salmonella vaccine strains are characterized, their advantages and drawbacks are noted. Great importance of the genetic safety of Salmonella attenuated strains to be controlled is emphasized, taking into account that they are also used as carrier strains for obtaining hybrid and gene-engineering (vector) vaccines carrying immunogenicity factors of other species of pathogenic microorganisms.

[The biological properties of Salmonella enteritidis strains isolated from different sources in the period of 1969-1989].

The study of S. enteritidis cultures of different origin, isolated at the period of 1969-1989, revealed that almost all strains isolated in 1988-1989 belonged to phagovar 1 and carried a plasmid with a molecular weight of 36 MD, while of the cultures isolated in 1969-1984 only one belonged to phagovar 1 and had a plasmid of 36 MD. All S.

[The role of the chromosome and its interaction with extrachromosomal determinants during the process of genetic control of bacterial pathogenicity].

The authors analyze current data on genetic control of the principal factors of pathogenicity of Shigella, Salmonella, Yersinia, Listeria and Proteus. They review the phases in the development of an infectious process and discuss problems in interaction of chromosomal and plasmid genes determining the pathogenicity of the said bacteria.

[The antilysozyme factor in Klebsiella pneumoniae: its nature, biological functions and genetic control].

The article deals with the data obtained as the result of the comprehensive study of K. pneumoniae antilysozyme factor, playing an essential role in the infectious pathology of weakened children and adults, as it was recently established. The study has revealed that the genes that determine the synthesis of the antilysozyme factor can be localized on the plasmid, tentatively designated pAlz60 and expressed in a wide circle of hosts of the family Enterobacteriaceae, belongs to type fi-, compatibility group Pl.

[The isolation and characteristics of the biological and genetic properties of neamin-resistant mutants of Salmonella abortus-ovis that are promising for vaccine creation].

Neamine-resistant mutants were obtained from S. abortus ovis virulent strain. These mutants were divided into three classes according to their sensitivity to streptomycin: mutants completely retaining their sensitivity, mutants sensitive to moderate and high doses of the antibiotic.

[Enterotoxigenicity of Salmonella strains of various origins].

The study of the enterotoxigenicity of S. typhimurium with the use of the skin test on rabbits (to detect the delayed permeability factor) has revealed that these strains produce an enterotoxin similar to Escherichia coli thermolabile enterotoxin (TLE). Study of the enterotoxic activity of lysates obtained from 39 S.

[Characteristics of Klebsiella pneumoniae plasmid bearing the markers of drug resistance and antilysozyme activity].

Electrophoretic study of the profile of plasmid DNA in agarose gel has shown the presence of a plasmid with a molecular weight of 55-60 MD in K. pneumoniae strains possessing antilysozyme activity. Plasmid pAlz60 of K.

[Plasmid profile types of virulent and avirulent strains of phase-I Shigella sonnei and their rough phase-II and R-form variants].

The study of S. sonnei in phase I, irrespective of their virulence, has revealed the existence of at least 3 types of profiles of large plasmids: (I)A having a single plasmid with a molecular weight of about 120 MD; (I)B having, alongside plasmid pSS120, a plasmid with a molecular weight of about 60 MD; (I)C, represented only by vaccine strain 6S, having three plasmids with molecular weights of about 80, 60 and 37 MD. The plasmid profiles of rough S.

[Mobilization of phase I plasmid in Shigella sonnei and stability of its inheritance in rough strains of Shigella and Escherichia].

The plasmid pSS120, determining the synthesis of species specific I phase antigen of Shigella sonnei is mobilized for genetic transfer into E. coli K12 recipient cells with the frequency 12-41%. The frequency depends on the type of mobilized plasmid and recipient strain.

[Plasmid characteristics of Salmonella strains of various origins].

Salmonella antibiotic-resistant strains, isolated from patients with hospital infections and from various environmental objects, showed lower virulence than antibiotic-sensitive strains in experiments on mice infected by intraperitoneal and enteral routes. Salmonella strains, sensitive to antimicrobial preparations, contained 1-2 plasmids, while those with multiple drug resistance contained 3-10 plasmids varying in their molecular weight. All these strains, with the exception of one laboratory strain, carried a plasmid with a molecular weight of about 60 Md.

[Genetic characteristics and protective properties of neamin-resistant mutant Salmonella typhimurium and S. dublin of the Nea(r) Str(s) and Nea(r) Str(r) 500 classes].

The genetic analysis of attenuated mutants, class Nea(r) Str(s), with the use of bacteriophage P 22 has shown that mutation rendering the mutants resistant to neamine is localized in gene nea A. In experiments with the intraperitoneal infection of mice, the appearance of this mutation in S. typhimurium and S.

[Genetic characteristics and trends in the spread of a new Shigella flexneri subserovar with the antigenic formula IV:7,8].

As the result of experiments with the conjugation of S. flexneri strains 4 belonging to an unusual subserovar (IV: 7,8) with Escherichia coli donor strains K12 Hfr C and Hfr H, as well as experiments with converting phages IV and 7,8, this new subserovar of S. flexneri 4, similarly to other S.

[Isolation and characteristics of the biological and genetic properties of neamin-resistant mutants of Salmonella typhimurium and Salmonella dublin candidates for vaccine creation].

Mutants, resistant to neamine and spectinomycin, have been isolated from S. typhimurium and S. dublin highly virulent strains.