Miniature hygrometric hot flush recorder as an objective indicator of hot flushes: a validation study.

Objective: Hot flushes are a very common symptom of menopause for which many women seek medical help. Accurate assessment of clinical severity and of the impact of treatment is limited by a lack of methods for objective hot flush recording. The aim of the current study is to test the diagnostic value of a miniature hygrometric hot flush recorder (HFR).

Luteinizing hormone-releasing hormone receptor antagonist may reduce postmenopausal flushing.

Objective: Hormone therapy (HT) is the most effective treatment of postmenopausal (PMP) flushing; however, its use is often contraindicated. As an alternative option, we explored the efficacy of the luteinizing hormone-releasing hormone (LHRH) receptor antagonist cetrorelix in women with severe PMP flushing.

Methods: We conducted an open-label treatment with cetrorelix 250 μg twice a day on 10 women with a baseline daily flush score of 15 or higher for a period of 4 to 6 weeks.