Enhanced analytical power of SDS-PAGE using machine learning algorithms.

We aim to demonstrate that a complex plant tissue protein mixture can be reliably "fingerprinted" by running conventional 1-D SDS-PAGE in bulk and analyzing gel banding patterns using machine learning methods. An unsupervised approach to filter noise and systemic biases (principal component analysis) was coupled to state-of-the-art supervised methods for classification (support vector machines) and attribute ranking (ReliefF) to improve tissue discrimination, visualization, and recognition of important gel regions.

Bcl-2 and MALT1 Genes are not involved in the oncogenesis of uterine tumors resembling ovarian sex cord tumors.

Uterine tumors resembling ovarian sex cord tumors (UTROSCT) are rare entities. They were described by Clement and Scully in 1976 who classified them into groups I and II. Group I comprises typical endometrial stromal neoplasms with focal areas resembling ovarian sex cord elements and group II are predominantly or completely composed of ovarian sex cord-like elements.

RecFOR function is required for DNA repair and recombination in a RecA loading-deficient recB mutant of Escherichia coli.

The RecA loading activity of the RecBCD enzyme, together with its helicase and 5' --> 3' exonuclease activities, is essential for recombination in Escherichia coli. One particular mutant in the nuclease catalytic center of RecB, i.e.