Publications by authors named "Petra M Konrad"
Background: In the immunosuppressed, detection of viral reactivation at the earliest convenience and molecular monitoring are of paramount importance. Nucleic acid extraction has a major impact on the reliability of results obtained from molecular assays.
Objectives: The aim of this study was to investigate the accuracy of the new EMAG nucleic acid extraction platform and to compare the performance of the new platform to that of the standard NucliSENS easyMAG instrument in the routine clinical laboratory.
Quantitation of EBV DNA has been shown to be a useful tool to identify and monitor patients with immunosuppression and high risk for EBV-associated disease. In this study, the analytical and clinical performance of the new Realquality RS-EBV Kit (AB Analitica, Padova, Italy) was investigated. The clinical performance was compared to that of the EBV R-gene (bioMerieux, Varilhes, France) assay.
View Article and Find Full Text PDFBackground: Accurate quantitation of hepatitis C virus (HCV) RNA is mandatory for the management of anti-HCV therapy.
Objectives: The genotype-dependent performance of the new commercially available VERSANT HCV RNA 1.0 Assay (kPCR) and the COBAS AmpliPrep/COBAS TaqMan HCV Quantitative Test, version 2.
Background: In hemodialysis (HD) patients, a decrease of serum HCV RNA concentration during HD has been reported.
Objectives: To evaluate the effect of two different extracorporeal blood treatments, HD and hemodiafiltration (HDF), on HCV RNA concentration under standardized conditions.
Study Design: Eleven chronic HD patients with chronic hepatitis C (CHC) and thirty-three non-uremic patients with CHC as controls were studied.