Publications by authors named "Petra Cacic"

Article Synopsis
  • The COVID-19 pandemic has significantly impacted public health and mental well-being, particularly among patients with inflammatory bowel disease (IBD), leading to changes in healthcare delivery and increased psychosocial stress.
  • A study conducted between April and June 2020 involved 132 IBD patients, revealing that a majority felt at high risk of contracting COVID-19 due to their condition, with concerns particularly prevalent among those on biologic therapies.
  • Female patients reported higher levels of stress and a greater need for psychological support, while a significant majority expressed satisfaction with the healthcare they received during this challenging time.
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Gastric cancer is related to high mortality rates and advanced disease stage at the time of diagnosis. Its carcinogenesis is extensively studied and is associated with genetic and epigenetic changes, changed the interaction between tumor and adjacent stromal cells, and changes in the microenvironment molecule status. Neural precursor cell-expressed developmentally down-regulated 9 (NEDD9) affects different signaling proteins and pathways, apoptosis, adhesion, cell migration, and invasiveness.

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Aims: We compared characteristics of patients with hyperglycemic hyperosmolar state (HHS) and patients with severe hyperglycemia without the signs of hyperosmolarity and ketoacidosis; analyzed long-term all-cause mortality and potential prognostic factors.

Methods: The studied population included 261 749 adults. HHS was diagnosed in patients with plasma glucose >33.

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Patients with type 2 diabetes mellitus have impaired ketogenesis due to high serum insulin and low growth hormone levels. Evidence exists that ketone bodies might improve kidney and cardiac function. In theory, improved ketogenesis in diabetics may have positive effects.

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