Ground State Nature and Nonlinear Squeezing of Gottesman-Kitaev-Preskill States.

The main bottleneck for universal quantum computation with traveling light is the preparation of Gottesman-Kitaev-Preskill states of sufficient quality. This is an extremely challenging task, experimental as well as theoretical, also because there is currently no single easily computable measure of quality for these states. We introduce such a measure, Gottesman-Kitaev-Preskill squeezing, and show how it is related to the current ways of characterizing the states.

Nonlinear feedforward enabling quantum computation.

Measurement-based quantum computation with optical time-domain multiplexing is a promising method to realize a quantum computer from the viewpoint of scalability. Fault tolerance and universality are also realizable by preparing appropriate resource quantum states and electro-optical feedforward that is altered based on measurement results. While linear feedforward has been realized and become a common experimental technique, nonlinear feedforward was unrealized until now.

Cubic nonlinear squeezing and its decoherence.

Squeezed states of the harmonic oscillator are a common resource in applications of quantum technology. If the noise is suppressed in a nonlinear combination of quadrature operators below threshold for all possible up-to-quadratic Hamiltonians, the quantum states are non-Gaussian and we refer to the noise reduction as nonlinear squeezing. Non-Gaussian aspects of quantum states are often more vulnerable to decoherence due to imperfections appearing in realistic experimental implementations.

Generation of quantum states with nonlinear squeezing by Kerr nonlinearity.

In quantum optics, squeezing corresponds to the process in which fluctuations of a quadrature operator are reduced below the shot noise limit. In turn, nonlinear squeezing can be defined as reduction of fluctuations related to nonlinear combination of quadrature operators. Quantum states with nonlinear squeezing are a necessary resource for deterministic implementation of high-order quadrature phase gates that are, in turn, sufficient for advanced quantum information processing.

p53 Binds Preferentially to Non-B DNA Structures Formed by the Pyrimidine-Rich Strands of GAA·TTC Trinucleotide Repeats Associated with Friedreich's Ataxia.

Expansions of trinucleotide repeats (TNRs) are associated with genetic disorders such as Friedreich's ataxia. The tumor suppressor p53 is a central regulator of cell fate in response to different types of insults. Sequence and structure-selective modes of DNA recognition are among the main attributes of p53 protein.

Loop-based subtraction of a single photon from a traveling beam of light.

Manipulating light by adding and subtracting individual photons is a powerful approach with a principal drawback: the operations are fundamentally probabilistic and the probability is often small. This limits not only the fundamental scalability but also the number of operations that can be applied in realistic experimental settings. We propose and analyze a loop-based technique which can significantly increase the probability of success while preserving the quality of the photon subtraction.

Qubit-mediated deterministic nonlinear gates for quantum oscillators.

Quantum nonlinear operations for harmonic oscillator systems play a key role in the development of analog quantum simulators and computers. Since strong highly nonlinear operations are often unavailable in the existing physical systems, it is a common practice to approximate them by using conditional measurement-induced methods. The conditional approach has several drawbacks, the most severe of which is the exponentially decreasing success rate of the strong and complex nonlinear operations.

Experimental characterization of a non-local convertor for quantum photonic networks.

We experimentally characterize a quantum photonic gate that is capable of converting multiqubit entangled states while acting only on two qubits. It is an important tool in large quantum networks, where it can be used for re-wiring of multipartite entangled states or for generating various entangled states required for specific tasks. The gate can be also used to generate quantum information processing resources, such as entanglement and discord.

p53 Specifically Binds Triplex DNA In Vitro and in Cells.

Triplex DNA is implicated in a wide range of biological activities, including regulation of gene expression and genomic instability leading to cancer. The tumor suppressor p53 is a central regulator of cell fate in response to different type of insults. Sequence and structure specific modes of DNA recognition are core attributes of the p53 protein.

Wild-type p53 binds to MYC promoter G-quadruplex.

G-quadruplexes are four-stranded nucleic acid structures that are implicated in the regulation of transcription, translation and replication. Genome regions enriched in putative G-quadruplex motifs include telomeres and gene promoters. Tumour suppressor p53 plays a critical role in regulatory pathways leading to cell cycle arrest, DNA repair and apoptosis.

p53 binds human telomeric G-quadruplex in vitro.

The tumor suppressor protein p53 is a key factor in genome stability and one of the most studied of DNA binding proteins. This is the first study on the interaction of wild-type p53 with guanine quadruplexes formed by the human telomere sequence. Using electromobility shift assay and ELISA, we show that p53 binding to telomeric G-quadruplexes increases with the number of telomeric repeats.

Noiseless Conditional Teleportation of a Single Photon.

We experimentally demonstrate the noiseless teleportation of a single photon by conditioning on quadrature Bell measurement results near the origin in phase space and thereby circumventing the photon loss that otherwise occurs even in optimal gain-tuned continuous-variable quantum teleportation. In general, thanks to this loss suppression, the noiseless conditional teleportation can preserve the negativity of the Wigner function for an arbitrary pure input state and an arbitrary pure entangled resource state. In our experiment, the positive value of the Wigner function at the origin for the unconditional output state, W(0,0)=0.

Exploring a new regime for processing optical qubits: squeezing and unsqueezing single photons.

We implement the squeezing operation as a genuine quantum gate, deterministically and reversibly acting "online" upon an input state no longer restricted to the set of Gaussian states. More specifically, by applying an efficient and robust squeezing operation for the first time to non-Gaussian states, we demonstrate a two-way conversion between a particlelike single-photon state and a wavelike superposition of coherent states. Our squeezing gate is reliable enough to preserve the negativities of the corresponding Wigner functions.

Generating superposition of up-to three photons for continuous variable quantum information processing.

We develop an experimental scheme based on a continuous-wave (cw) laser for generating arbitrary superpositions of photon number states. In this experiment, we successfully generate superposition states of zero to three photons, namely advanced versions of superpositions of two and three coherent states. They are fully compatible with developed quantum teleportation and measurement-based quantum operations with cw lasers.