Publications by authors named "Petr L Shcherbakov"
Article Synopsis
- Crohn's disease is linked to imbalances in gut bacteria, specifically with an increase in certain types of E. coli, and more research is needed to understand their role.
- A metagenomic study of Crohn's patients showed that the gut microbiomes varied significantly between individuals, revealing high genetic diversity in E. coli strains.
- The findings suggest that understanding the genetic diversity of these bacteria can help develop better prevention and treatment options for Crohn's disease.
Background: Alcohol abuse has deleterious effects on human health by disrupting the functions of many organs and systems. Gut microbiota has been implicated in the pathogenesis of alcohol-related liver diseases, with its composition manifesting expressed dysbiosis in patients suffering from alcoholic dependence. Due to its inherent plasticity, gut microbiota is an important target for prevention and treatment of these diseases.
View Article and Find Full Text PDFAlcoholism is associated with significant changes in gut microbiota composition. Metagenomic sequencing allows to assess the altered abundance levels of bacterial taxa and genes in a culture-independent way. We collected 99 stool samples from the patients with alcoholic dependence syndrome (=72) and alcoholic liver cirrhosis (=27).
View Article and Find Full Text PDFThe microbial community of the human gut has a crucial role in sustaining host homeostasis. High-throughput DNA sequencing has delineated the structural and functional configurations of gut metagenomes in world populations. The microbiota of the Russian population is of particular interest to researchers, because Russia encompasses a uniquely wide range of environmental conditions and ethnogeographical cohorts.
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