Publications by authors named "Petr Holly"

Background: Head tremor poses diagnostic problems, especially when present as an isolated or predominant symptom.

Objectives: To assess how maneuvers activating upper limb postural tremor can help differentiate head tremor in essential tremor (ET) from dystonic tremor (DT) in cervical dystonia.

Methods: 48 patients with head tremor (25 ET, 23 DT), underwent clinical examination and accelerometric evaluation of head and upper limb tremor during routine tremor-inducing tasks.

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Article Synopsis
  • Various methods are used to assess tremor severity in essential tremor (ET), but their relationship to daily living impairments isn't fully understood.
  • The study examined 40 ET patients to find out which predictors are most effective for evaluating their ability to perform daily activities using several assessment tools.
  • Results showed that the Essential Tremor Rating Assessment Scale (TETRAS) Performance Subscale was able to explain nearly 70% of daily activity impairment in ET patients, and adding other assessments didn’t significantly improve predictions.
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Pathogenic variants in are one of the most common genetic risk factors for Parkinson's disease (PD). Recently, the lesser-known p.L1795F variant was proposed as a strong genetic risk factor for PD, however, further families are currently lacking in literature.

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Introduction: Head tremor is a common symptom of essential tremor (ET) and cervical dystonia (CD). In clinical practice, it is often difficult to distinguish between these two conditions, especially in cases where head tremor predominates.

Objectives: To investigate which clinical and instrumental methods best differentiate ET and CD in patients with head tremor.

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