Real-time prediction of intradialytic relative blood volume: a proof-of-concept for integrated cloud computing infrastructure.

Background: Inadequate refilling from extravascular compartments during hemodialysis can lead to intradialytic symptoms, such as hypotension, nausea, vomiting, and cramping/myalgia. Relative blood volume (RBV) plays an important role in adapting the ultrafiltration rate which in turn has a positive effect on intradialytic symptoms. It has been clinically challenging to identify changes RBV in real time to proactively intervene and reduce potential negative consequences of volume depletion.

Arterial oxygen saturation and hypoxemia in hemodialysis patients with COVID-19.

Background: Maintenance hemodialysis (MHD) patients are particularly vulnerable to coronavirus disease 2019 (COVID-19), a viral disease that may cause interstitial pneumonia, impaired alveolar gas exchange and hypoxemia. We ascertained the time course of intradialytic arterial oxygen saturation (SaO) in MHD patients between 4 weeks pre-diagnosis and the week post-diagnosis of COVID-19.

Methods: We conducted a quality improvement project in confirmed COVID-19 in-center MHD patients from 11 dialysis facilities.