Publications by authors named "Peter Vorwald"

Introduction: Antireflux surgery is commonly associated with significant recurrence and complication rates, and several surgical techniques have been proposed to minimize them. The aim of this study is to evaluate the results of a fundoplication with extensive dissection of the esophagogastric junction 1 and 3 years after the procedure.

Methods: Retrospective observational study including 178 patients with gastroesophageal reflux disease or hiatal hernia who underwent fundoplication with extensive dissection of the esophagogastric junction between 2015 and 2020.

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Objective: Certain diseases such as obesity and cancer can cause impaired wound healing. Adipose tissue derived stem cells (ASCs) are a novel field of research. Many studies have evidenced their high degree of safety and potential for wound repair due to their immunomodulatory and tissue-regeneration properties.

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Background: Core outcome sets (COS) should be relevant to key stakeholders and widely applicable and usable. Ideally, they are developed for international use to allow optimal data synthesis from trials. Electronic Delphi surveys are commonly used to facilitate global participation; however, this has limitations.

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Article Synopsis
  • - The study compares adipose-derived mesenchymal stem cells (MSCs) from different fat sources (omentum and subcutaneous) in patients with morbid obesity, cancer, and healthy donors to assess their potential for clinical use.
  • - Researchers found that while MSCs from obese and cancer patients have a similar mesenchymal phenotype and proliferation capacity as those from healthy donors, their differentiation potential and cytokine secretion vary significantly depending on the patient's pathology and fat source.
  • - Specifically, omental MSCs from cancer patients exhibited higher anti-inflammatory properties but lower cell generation, whereas MSCs from both obesity and cancer patients showed alterations that could limit their therapeutic effectiveness.
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Article Synopsis
  • The COVID-19 pandemic significantly impacted patient care, leading to temporary halts in essential cancer surgeries, with heightened concerns about risks during the reintroduction of complex surgical procedures.
  • An international study analyzed 158 patients undergoing open and minimally invasive oesophago-gastric surgeries across nine European centers during a high COVID-19 incidence period, focusing on 30-day COVID-19-related mortality and staff health.
  • Findings indicated no post-operative COVID-19 cases among patients, though two healthcare workers experienced mild symptoms, suggesting that implemented safety measures were effective in minimizing infection risks during surgeries.
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Background: The best alimentary and biliopancreatic limb (BPL) lengths in the Roux-en-Y gastric bypass (RYGB) still remain unclear. The aim of this study was to compare the effect of a BPL of 70 vs 120 cm, with a constant AL of 150 cm on long-term weight loss, remission of comorbidities, and supplementation needs after RYGB.

Patients And Methods: A prospective randomized study of morbidly obese patients undergoing RYGB was performed.

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Background: Up to 22% of the patients, after laparoscopic Roux-en-Y gastric bypass (LRYGB) can complain about gastroesophageal reflux disease (GERD) symptoms, there is little evidence about the most effective treatment of this situation.

Materials And Method: This video shows a laparoscopic reintervention after a LRYGB in a 42-year-old woman presenting with untreatable GERD. GERD was treated with maximum doses of PPIs with no effect on the symptoms; the patient had a 24-h pH and impedance manometry that showed an acid and non-acid reflux, and for that reason, we decided to perform a laparoscopic fundoplication.

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ERAS is a multimodal perioperative care program which replaces traditional practices concerning analgesia, intravenous fluids, nutrition, mobilization as well as a number of other perioperative items, whose implementation is supported by evidence-based best practices. According to the RICA guidelines published in 2015, a review of the literature and the consensus established at a multidisciplinary meeting in 2015, we present a protocol that contains the basic procedures of an ERAS pathway for resective esophageal surgery. The measures involved in this ERAS pathway are structured into 3areas: preoperative, perioperative and postoperative.

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This video shows a laparoscopic reintervention after an open, vertical banded gastroplasty in a 39-year-old woman presenting with untreatable GERD.

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Introduction: Enhanced recovery after surgery is a modality of perioperative management with the purpose of improving results and providing a faster recovery of patients. This kind of protocol has been applied frequently in colorectal surgery, presenting less available experience and evidence in gastric surgery.

Methods: According to the RICA guidelines published in 2015, a review of the bibliography and the consensus established in a multidisciplinary meeting in Zaragoza on the 9th of October 2015, we present a protocol that contains the basic procedures of fast-track for resective gastric surgery.

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Purpose: Caudal-related homeobox transcription factor 2 (CDX2) has recently been proposed as a prognostic factor for gastric carcinoma. However and to the best of our knowledge, no previous report has analyzed CDX2 expression in patients with gastric adenocarcinoma receiving neoadjuvant therapy (NAT).

Patients, Materials And Methods: This is a retrospective cohort study to analyze the potential role of CDX2 expression to predict response to NAT and prognosis.

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Background. Biliobronchial fistula (BBF) is a rare complication in the natural history of liver hydatid disease by Echinococcus granulosus. We present a case of BBF after resection of a giant liver hydatid cyst in a 72-year-old woman.

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