Cyclosporin as an adjunct to glaucoma filtration surgery.

Purpose: Current adjunctive therapies to glaucoma surgery have unreliable effects, are toxic, and have numerous late complications associated with their use. This study examined whether topical cyclosporin (CsA) prolongs bleb survival after glaucoma filtration surgery.

Methods: Anesthetized white New Zealand rabbits underwent glaucoma filtration surgery with a drainage tube.

Confocal microscopy used as the definitive, early diagnostic method in Chandler syndrome.

Purpose: To report the early, rapid diagnosis of the Chandler variant of the iridocorneal endothelial (ICE) syndrome using confocal light microscopy.

Methods: A 62-year-old man with a long history of unilateral glaucoma reported progressively blurred vision in his right eye. Examination of both eyes included visual acuity, slit-lamp examination, pneumotonometry, visual field, gonioscopy, and confocal microscopy.

Cyclosporin-augmented laser peripheral iridoplasty.

Background And Objective: Almost all patients develop iritis following argon laser peripheral iridoplasty. Numerous adverse effects, particularly elevated intraocular pressure (IOP) and reduced microbial resistance, complicate therapy with topical corticosteroids. An immunomodulator, such as cyclosporin A (CsA), avoids these undesirable effects, yet may suppress ocular inflammation.