Effect of NaF, AmF, KF gels and NaF toothpaste combined with a saliva substitute on dentin lesions in vitro.

Objective: The aim of the present in vitro study was to evaluate the remineralizing effects of NaF, AmF, KF gels and NaF toothpaste in combination with a potentially demineralizing saliva substitute (Glandosane; pH = 5.1) being widely used in Germany.

Methods: In each of 120 dentin specimens, three artificial lesions were created.

Conservative, Surgical, and Prosthetic Treatment of a Patient with a Periapical Lesion Associated with an Atypical Intraoral Sinus Tract.

This report describes a clinical case with an atypical intraoral sinus tract formation from diagnosis and treatment to short-term outcome and definitive prosthetic rehabilitation. In detail, the patient underwent conservative nonsurgical root canal treatment followed by guided bone augmentation of the regions involved in periapical inflammation and sinus tract formation. The removal of the inflammatory source of the lesion as well as the affected tissue clearly led to a healing of the surrounding bone tissues.

Saliva substitutes in combination with high-fluoride gel on dentin remineralization.

Objective: This study aimed to determine whether the application of a high-fluoride gel could increase the remineralization of subsurface dentin lesions stored in saliva substitutes.

Materials And Methods: Demineralized bovine dentin specimens were stored in mineral water (W), Glandosane (G), or modified Saliva natura (SN). Different treatments were applied twice daily: no treatment, Elmex sensitive mouth rinse (E), ProSchmelz gel (P), Duraphat toothpaste (D), ED, PD, and EPD.

Effects of regular and highly fluoridated toothpastes in combination with saliva substitutes on artificial enamel caries lesions differing in mineral content.

Objective: For patients with hyposalivation fluorides are supportive to prevent caries lesions. Remineralization of subsurface lesions might be improved by toothpastes containing 5000 μgF(-)/g compared with those having 1400 μgF(-)/g. This could be influenced by the degree of baseline mineralization.

The influence of daily application of fluoride products on subsurface bovine enamel lesions stored in saliva substitutes.

Purpose: To evaluate in the laboratory the effects of daily fluoride applications on remineralization of subsurface bovine enamel lesions stored in different saliva substitutes.

Methods: Enamel specimens were prepared (n = 144) and demineralized (subsurface lesions; 37 degrees C; pH 4.95; 10 days).

Remineralization of bovine enamel subsurface lesions: effects of different calcium-phosphate saturations in buffered aqueous solutions.

Objective: To evaluate the remineralizing effects of aqueous phosphate-buffered solutions using various saturations with respect to octacalcium phosphate or brushite (OCP/DCPD) on bovine enamel subsurface lesions.

Method And Materials: Demineralized specimens (n=18 per group) were exposed to one of six phosphate-buffered solutions with theoretical OCP saturations of S0.83, S1.

Enamel and dentine remineralization by nano-hydroxyapatite toothpastes.

Objectives: This in vitro study evaluated the effects of nano-hydroxyapatite (n-HAp) toothpastes on remineralization of bovine enamel and dentine subsurface lesions.

Methods: Specimens were demineralized, randomly divided into five groups, and exposed to an aqueous remineralizing solution for two and five weeks (37 °C). Brushing procedures were performed with the respective toothpaste/storage solution slurry twice daily (2 × 5 s; total contact time of the slurries 2 × 120s/d): storage in remineralizing solution only (0); additional brushing with B (20 wt% zinc carbonate nano-hydroxyapatite, ZnCO(3)/n-HAp); BS (24 wt% ZnCO(3)/n-HAp); E (0.

Design of a randomized controlled double-blind crossover clinical trial to assess the effects of saliva substitutes on bovine enamel and dentin in situ.

Background: Hyposalivation is caused by various syndromes, diabetes, drugs, inflammation, infection, or radiotherapy of the salivary glands. Patients with hyposalivation often show an increased caries incidence. Moreover, hyposalivation is frequently accompanied by oral discomfort and impaired oral functions, and saliva substitutes are widely used to alleviate oral symptoms.

Mineral distribution of artificial dentinal caries lesions after treatment with fluoride agents in combination with saliva substitutes.

Objective: Some saliva substitutes have been shown to demineralize dentine in vitro. This effect is counteracted by the application of various fluorides. In contrast, remineralizing saliva substitutes might be supported by these treatments, depending on the dynamics during remineralization.

Effect of saliva substitutes in combination with fluorides on remineralization of subsurface dentin lesions.

Purpose: Saliva substitutes are prescribed to patients suffering from radiation-induced hyposalivation to alleviate oral complaints; however, some available products have shown to demineralize dentin. The purpose of this in vitro study was to evaluate the effects of two saliva substitutes in combination or not with fluoridation on remineralization of bovine dentin subsurface lesions.

Materials And Methods: Dentin specimens were demineralized, and stored in either mineral water (control; volvic, danone), Glandosane (cell pharm), or modified Saliva natura (SN, Medac) for 5 weeks (37° C).

Effect of fluoride gels and mouthrinses in combination with saliva substitutes on demineralised bovine enamel in vitro.

Objective: Besides the use of saliva substitutes, patients suffering from hyposalivation are instructed to apply fluoride products to prevent caries. Some saliva substitutes have been shown to demineralise enamel; an effect that might be counteracted by the application of fluoride gels or mouthrinses. Combined use of these products with remineralising or neutral saliva substitutes might result in more pronounced remineralisation.

Etiologic factors of hyposalivation and consequences for oral health.

Hyposalivation is represented by a reduced salivary flow rate and can be caused by etiologic factors such as systemic diseases and intake of various medications or by radiotherapy following head and neck cancer. The aim of this review was to compile data about the qualitative and quantitative changes of salivary components during hyposalivation, and to summarize their consequences for oral health. A Medline/PubMed/Scopus search was conducted to identify and summarize articles published in English and German that reported on etiology of hyposalivation and changes in the salivary composition due to hyposalivation of different origins.

Saliva substitute in combination with high-concentrated fluoride toothpaste: effects on demineralised dentin in vitro.

Objectives: The aim of this in vitro study was to assess the effects of saliva substitutes (modified with respect to calcium, phosphates, and fluorides) in combination with a high-concentrated fluoride toothpaste on demineralised dentin.

Methods: Before and after demineralisation of bovine dentin specimens (subsurface lesions; 37 degrees C, pH 5.0, 5 d), one-quarter of each specimen's surface was covered with nail varnish (control of sound/demineralised tissue).

Effects of regular and whitening dentifrices on remineralization of bovine enamel in vitro.

Objective: To compare in vitro the remineralizing effects of different regular dentifrices and whitening dentifrices (containing pyrophosphates) on predemineralized enamel.

Method And Materials: Specimens from 84 bovine incisors were embedded in epoxy resin, partly covered with nail varnish, and demineralized in a lactic acid solution (37 degrees C, pH 5.0, 8 days).

Effect of fluoridated bleaching gels on the remineralization of predemineralized bovine enamel in vitro.

Objectives: This study evaluated possible differences regarding the remineralization of predemineralized enamel after exposure to fluoridated or non-fluoridated bleaching gels.

Methods: 120 enamel specimens were prepared from sixty bovine incisors; before and after demineralization (37 degrees C; pH 4.95; 10d), one-quarter of each specimen's surface was covered with nail varnish (control sound/demineralized).

Effect of polymers used in saliva substitutes on demineralized bovine enamel and dentin.

Purpose: To evaluate the effects of porcine mucin- and carboxymethylcellulose-based (CMC) solutions on the inhibition of demineralization of pre-demineralized bovine enamel and dentin in vitro. Additionally the sugar substitutes sorbit or xylit were added to the various solutions.

Methods: 54 enamel and dentin samples were prepared from 14 freshly extracted permanent bovine central incisors.

[The role of COX-2 in dentistry. Past or future?].

Nonsteroidal anti-inflammatory drugs (NSAIDs) are widely used to inhibit cyclooxygenase (COX) activity within the scope of pain and inflammation therapy. Although these pharmaceuticals are effective in the treatment of pain and inflammation, their routine and long-term administration is limited due to their side effects (e.g.

Linseed based saliva substitutes and their effect on mineral dissolution of predemineralized bovine dentin in vitro.

Objectives: Polymers used in saliva substitutes might inhibit remineralization. The present study evaluated the effects of various calcium, phosphate, and fluoride concentrations of linseed based solutions on the mineral loss of predemineralized bovine dentin in vitro.

Methods: Dentin specimens were prepared, embedded and polished.