Effect of PLGA raw materials on in vitro and in vivo performance of drug-loaded microspheres.

Poly(lactide-co-glycolide) and poly(lactic-co-glycolic acids) (PLGAs) play a critical role in the development of commercial long-acting injectable microsphere formulations. However, very little information is available describing the impact of PLGA manufacturer and monomer distribution along the polymer chain (e.g.

Predicting Single Neuron Responses of the Primary Visual Cortex with Deep Learning Model.

Modeling neuron responses to stimuli can shed light on next-generation technologies such as brain-chip interfaces. Furthermore, high-performing models can serve to help formulate hypotheses and reveal the mechanisms underlying neural responses. Here the state-of-the-art computational model is presented for predicting single neuron responses to natural stimuli in the primary visual cortex (V1) of mice.