The two-faceted nature of impulsivity in patients with borderline personality disorder and substance use disorder.

Background: Impulsivity, which has been the subject of extensive debate in psychiatric research, is a clinically important concept, especially with respect to Borderline Personality Disorder (BPD) and Substance Use Disorders (SUD). The current study aims to examine the presence of two aspects of impulsivity (self-reported impulsivity and delay discounting) in patients with BPD, SUD (alcohol use=AUD or drug use=DUD) and the combination of both disorders (BPD+SUD).

Methods: Patients were recruited from eight different mental health treatment service facilities.

Early experience with Suboxone maintenance therapy in Hungary.

Background: Suboxone (Buprenorphine/naloxone) is a novel drug used in opiate substitution therapy. In Hungary, it was introduced in November 2007. Suboxone is a product for sublingual administration containing the partial mu-receptor agonist buprenorphine and antagonist naloxone in a 4:1 ratio.

The individual adjustment method of sleep spindle analysis: methodological improvements and roots in the fingerprint paradigm.

Evidence supports the robustness and stability of individual differences in non-rapid eye movement (NREM) sleep electroencephalogram (EEG) spectra with a special emphasis on the 9-16 Hz range corresponding to sleep spindle activity. These differences cast doubt on the universal validity of sleep spindle analysis methods based on strict amplitude and frequency criteria or a set of templates of natural spindles. We aim to improve sleep spindle analysis by the individual adjustments of frequency and amplitude criteria, the use of a minimum set of a priori knowledge, and by clear dissections of slow- and fast sleep spindles as well as to transcend the concept of visual inspection as being the ultimate test of the method's validity.

Prediction of general mental ability based on neural oscillation measures of sleep.

The usual assessment of general mental ability (or intelligence) is based on performance attained in reasoning and problem-solving tasks. Differences in general mental ability have been associated with event-related neural activity patterns of the wakeful working brain or physical, chemical and electrical brain features measured during wakeful resting conditions. Recent evidences suggest that specific sleep electroencephalogram oscillations are related to wakeful cognitive performances.