A randomized controlled trial of cognitive control training (CCT) as an add-on treatment for late-life depression: a study protocol.

Background: Already a major health concern, late-life depression (LLD) is expected to form an increasing problem in the aging population. Moreover, despite current treatments, LLD is associated with a poor long-term prognosis and high rate of chronicity. Treatment provision and treatment accordingly warrant improvement, where add-on treatments might contribute to the efficacy of conventional therapies.

Exercise enhances: study protocol of a randomized controlled trial on aerobic exercise as depression treatment augmentation.

Background: Major depressive disorder (MDD) is a considerable public health concern. In spite of evidence-based treatments for MDD, many patients do not improve and relapse is common. Therefore, improving treatment outcomes is much needed and adjunct exercise treatment may have great potential.