Effects of Pandemic Response Measures on Crime Counts in English and Welsh Local Authorities.

The global response to the COVID-19 pandemic between January 2020 and late 2021 saw extraordinary measures such as lockdowns and other restrictions being placed on citizens' movements in many of the world's major cities. In many of these cities, lockdowns required citizens to stay at home; non-essential business premises were closed, and movement was severely restricted. In this paper, we investigate the effect of these lockdowns and other pandemic response measures on crime counts within the local authorities of England and Wales.

Intestinal failure-associated liver disease: Current challenges in screening, diagnosis, and parenteral nutrition considerations.

Intestinal failure-associated liver disease (IFALD) is a serious life-limiting complication that can occur throughout the clinical course of intestinal failure and its management by parenteral nutrition (PN). Despite this, there is a lack of a standardized definition for IFALD, which makes this insidious condition increasingly difficult to screen and diagnose in clinical practice. Attenuating the progression of liver disease before the onset of liver failure is key to improving morbidity and mortality in these patients.

A method for creating complex real-world networks using ESRI Shapefiles.

NetworkX are probably the most popular approaches in industry for creating hapefiles (Geospatial Vector Data In this study,•We outline a flexible method that can be used to easily create graphical network representations in NetworkX or using road network topology data stored in ESRI Shapefiles• successfully transform the ESRI Shapefile data into the compatible format for graph analysis libraries like OSMnx and NetworkX.• without distorting the actual structure of the graph.This method will allow efficiencies of different sizes and topologies.

Continent-wide declines in shallow reef life over a decade of ocean warming.

Human society is dependent on nature, but whether our ecological foundations are at risk remains unknown in the absence of systematic monitoring of species' populations. Knowledge of species fluctuations is particularly inadequate in the marine realm. Here we assess the population trends of 1,057 common shallow reef species from multiple phyla at 1,636 sites around Australia over the past decade.

Tracking widespread climate-driven change on temperate and tropical reefs.

Warming seas, marine heatwaves, and habitat degradation are increasingly widespread phenomena affecting marine biodiversity, yet our understanding of their broader impacts is largely derived from collective insights from independent localized studies. Insufficient systematic broadscale monitoring limits our understanding of the true extent of these impacts and our capacity to track these at scales relevant to national policies and international agreements. Using an extensive time series of co-located reef fish community structure and habitat data spanning 12 years and the entire Australian continent, we found that reef fish community responses to changing temperatures and habitats are dynamic and widespread but regionally patchy.

Do gastroenterologists have medical inertia towards coeliac disease? A UK multicentre secondary care study.

Objective: This study aimed to assess if there is secondary care medical inertia towards coeliac disease (CD).

Design: Group (1): Time from primary care presentation to diagnostic endoscopy was quantified in 151 adult patients with a positive endomysial antibody test and compared with 92 adult patients with histologically proven inflammatory bowel disease (IBD). Group (2): Across four hospitals, duodenal biopsy reports for suspected CD were reviewed (n=1423).

Office-Based Point of Care Testing (IgA/IgG-Deamidated Gliadin Peptide) for Celiac Disease.

Objectives: Celiac disease (CD) is common yet under-detected. A point of care test (POCT) may improve CD detection. We aimed to assess the diagnostic performance of an IgA/IgG-deamidated gliadin peptide (DGP)-based POCT for CD detection, patient acceptability, and inter-observer variability of the POCT results.

A comparison study between Magniview and high definition white light endoscopy in detecting villous atrophy and coeliac disease: A single centre pilot study.

Background And Aims: Coeliac disease may be missed at gastroscopy. We aimed to assess the sensitivity of Pentax optical zoom technology endoscopes in detecting duodenal villous atrophy and the ease of image interpretation by non-coeliac specialists.

Method: All patients attending for a gastroscopy were assessed for endoscopic villous atrophy in part one and two of the duodenum with high definition white light endoscopy and magnification endoscopy.

The Role of an IgA/IgG-Deamidated Gliadin Peptide Point-of-Care Test in Predicting Persistent Villous Atrophy in Patients With Celiac Disease on a Gluten-Free Diet.

Objectives: Mucosal healing is important in celiac disease (CD) for the prevention of complications. However, obtaining duodenal biopsies is invasive, and there is currently no reliable surrogate marker for histological remission in clinical practice. We aimed to assess the role of a point-of-care test (POCT) based on IgA/IgG-deamidated gliadin peptide, in detecting persistent villous atrophy (VA) in CD.

Using Crowdsourced Trajectories for Automated OSM Data Entry Approach.

The concept of crowdsourcing is nowadays extensively used to refer to the collection of data and the generation of information by large groups of users/contributors. OpenStreetMap (OSM) is a very successful example of a crowd-sourced geospatial data project. Unfortunately, it is often the case that OSM contributor inputs (including geometry and attribute data inserts, deletions and updates) have been found to be inaccurate, incomplete, inconsistent or vague.

'Pre-endoscopy point of care test (Simtomax- IgA/IgG-Deamidated Gliadin Peptide) for coeliac disease in iron deficiency anaemia: diagnostic accuracy and a cost saving economic model'.

Background: International guidelines recommend coeliac serology in iron deficiency anaemia, and duodenal biopsy for those tested positive to detect coeliac disease. However, pre-endoscopy serology is often unavailable, thus committing endoscopists to take routine duodenal biopsies. Some endoscopists consider duodenal biopsy mandatory in anaemia to exclude other pathologies.

Crowdsourcing: It Matters Who the Crowd Are. The Impacts of between Group Variations in Recording Land Cover.

Volunteered geographical information (VGI) and citizen science have become important sources data for much scientific research. In the domain of land cover, crowdsourcing can provide a high temporal resolution data to support different analyses of landscape processes. However, the scientists may have little control over what gets recorded by the crowd, providing a potential source of error and uncertainty.

High definition endoscopy with or without I-Scan increases the detection of celiac disease during routine endoscopy.

Background And Aims: Celiac disease remains underdiagnosed at endoscopy. We aimed to assess the utility of I-Scan (virtual chromo-endoscopy) to improve sensitivity of endoscopy to detect markers of villous atrophy in this condition.

Methods: Patients from 2 UK hospitals were studied in 3 groups.

Clinical and Immunologic Features of Ultra-Short Celiac Disease.

Background & Aims: The clinical effects of gluten-sensitive enteropathy with villous atrophy limited to the duodenal bulb (D1) have not been delineated in adults with celiac disease. We investigated the sensitivity of D1 biopsy analysis in the detection of celiac disease, the number and sites of biopsies required to detect ultra-short celiac disease (USCD, villous atrophy limited to D1), and the clinical phenotype of USCD.

Methods: We performed a prospective study of 1378 patients (mean age, 50.

Neurological Dysfunction in Coeliac Disease and Non-Coeliac Gluten Sensitivity.

Objectives: Non-coeliac gluten sensitivity (NCGS) refers to patients with primarily gastrointestinal symptoms without enteropathy that symptomatically benefit from gluten-free diet (GFD). Little is known about its pathophysiology, propensity to neurological manifestations, and if these differ from patients with coeliac disease (CD). We investigated the clinical and immunological characteristics of patients presenting with neurological manifestations with CD and those with NCGS.

Celiac Disease and Double-Balloon Enteroscopy: What Can We Achieve?: The Experience of 2 European Tertiary Referral Centers.

Background: Indications to double-balloon enteroscopy (DBE) are not standardized in celiac disease (CD).

Goals: To evaluate the clinical usefulness of DBE in complicated CD.

Study: DBE findings in celiac patients with suspected small bowel (SB) complications were retrospectively evaluated in 2 tertiary referral centers (Milan and Sheffield).

Cost and availability of gluten-free food in the UK: in store and online.

Objective: Coeliac disease (CD) is a lifelong condition requiring strict adherence to a gluten-free (GF) diet and good availability of GF foods is critical to this. Patients with CD from lower socioeconomic groups are recognised to have higher treatment burden and higher food costs may impact this. Therefore, we aimed to assess the availability and cost of GF food in supermarkets and via the internet.

Gastro-oesophageal reflux symptoms and coeliac disease: no role for routine duodenal biopsy.

Background: Coeliac disease (CD) has been linked to gastro-oesophageal reflux disease (GORD). Previous studies have demonstrated an increased prevalence of reflux in patients with CD. However data on the risk for CD in patients presenting with reflux are conflicting.

Increased Detection of Celiac Disease With Measurement of Deamidated Gliadin Peptide Antibody Before Endoscopy.

Background & Aims: Celiac disease is underdiagnosed. Many patients are examined by endoscopy, but celiac disease is missed or not detected. We evaluated the accuracy of finger prick-based point-of-care tests in the detection of celiac disease and developed an algorithm for diagnosis.