Publications by authors named "Peter M Richieri"
Article Synopsis
- Aberrant expression of repeat RNAs in pancreatic ductal adenocarcinoma (PDAC) resembles viral responses, affecting tumor cells and their microenvironment.
- A study on 46 primary tumors revealed that high repeat RNA levels correlate with changes in cell identity in both PDAC cells and cancer-associated fibroblasts (CAFs).
- The distinct immune signaling pathways in PDAC and CAFs, particularly involving interferon regulatory factor 3 (IRF3), highlight how these viral-like responses impact cellular flexibility and interactions within the tumor environment.
