Publications by authors named "Peter M Macharia"

Article Synopsis
  • - The study aimed to determine how common double burden of malnutrition (DBM) and triple burden of malnutrition (TBM) are among mother-child pairs in Malawi, while also examining how these issues vary by location and various factors.
  • - Utilizing data from the 2015-2016 Malawi Demographic and Health Survey, researchers found that about 5.5% of mother-child pairs experienced DBM and 3.1% faced TBM, with higher rates occurring in urban areas.
  • - The findings revealed that wealthier communities had a threefold increase in DBM, while education improved outcomes, as women with some education showed a 60% lower risk of TBM. This suggests that targeted interventions should
View Article and Find Full Text PDF

Background: Understanding diagnostic capacities is essential to addressing healthcare provision and inequity, particularly in low-income and middle-income countries. This study used routine data to assess trends in rapid diagnostic test (RDT) reporting, supplies and unmet needs across national and 47 subnational (county) levels in Kenya.

Methods: We extracted facility-level RDT data for 19 tests (2018-2020) from the Kenya District Health Information System, linked to 13 373 geocoded facilities.

View Article and Find Full Text PDF

Google Maps Directions Application Programming Interface (the API) and AccessMod tools are increasingly being used to estimate travel time to healthcare. However, no formal comparison of estimates from the tools has been conducted. We modelled and compared median travel time (MTT) to comprehensive emergency obstetric care (CEmOC) using both tools in three Nigerian conurbations (Kano, Port-Harcourt, and Lagos).

View Article and Find Full Text PDF
Article Synopsis
  • - The study investigates how geographical factors impact breast cancer survival rates in sub-Saharan Africa, highlighting the need for improved healthcare access in these regions.
  • - Researchers analyzed data from over 2,000 women diagnosed with breast cancer, revealing that those in rural areas had significantly lower 4-year survival rates (39%) compared to those in urban areas (49%).
  • - Findings indicate that women living more than an hour from a hospital faced even worse outcomes, emphasizing the urgent need for interventions to address these healthcare disparities.
View Article and Find Full Text PDF

Background: Better accessibility for emergency obstetric care facilities can substantially reduce maternal and perinatal deaths. However, pregnant women and girls living in urban settings face additional complex challenges travelling to facilities. We aimed to assess the geographical accessibility of the three nearest functional public and private comprehensive emergency obstetric care facilities in the 15 largest Nigerian cities via a novel approach that uses closer-to-reality travel time estimates than traditional model-based approaches.

View Article and Find Full Text PDF

Background: Better geographical accessibility to comprehensive emergency obstetric care (CEmOC) facilities can significantly improve pregnancy outcomes. However, with other factors, such as affordability critical for care access, it is important to explore accessibility across groups. We assessed CEmOC geographical accessibility by wealth status in the 15 most-populated Nigerian cities.

View Article and Find Full Text PDF

Assessing geographic accessibility to healthcare is essential to identify communities that have been left behind. Smartphone mobility data now enables the study of healthcare accessibility over a global scale, providing estimates of actual travel times to access care.

View Article and Find Full Text PDF
Article Synopsis
  • Breast cancer is the most common cancer among women in Namibia, highlighting the need to understand racial disparities in their treatment and outcomes to better address and reduce mortality rates.
  • The study aimed to track the entire breast cancer journey of Namibian women, categorizing data by race according to the World Health Organization’s framework.
  • Findings showed that three-year overall survival rates varied significantly by ethnicity, with Black women having the lowest survival rate at 60%, compared to 80% for those of mixed ancestry and 89% for White women, necessitating targeted interventions.
View Article and Find Full Text PDF

Travel time estimation accounting for on-the-ground realities between the location where a need for emergency obstetric care (EmOC) arises and the health facility capable of providing EmOC is essential for improving pregnancy outcomes. Current understanding of travel time to care is inadequate in many urban areas of Africa, where short distances obscure long travel times and travel times can vary by time of day and road conditions. Here, we describe a database of travel times to comprehensive EmOC facilities in the 15 most populated extended urban areas of Nigeria.

View Article and Find Full Text PDF

The demographic, ecological and socioeconomic changes associated with urbanisation are linked to changes in disease incidence, health service provision and mortality. These effects are heterogeneous between and within urban areas, yet without a clear definition of what constitutes an 'urban' area, their measurement and comparison are constrained. The definitions used vary between countries and over time hindering analyses of the relationship between urbanisation and health outcomes, evaluation of policy actions and results in uncertainties in estimated differences.

View Article and Find Full Text PDF

Objectives: To propose a novel framework for COVID-19 vaccine allocation based on three components of Vulnerability, Vaccination, and Values (3Vs).

Methods: A combination of geospatial data analysis and artificial intelligence methods for evaluating vulnerability factors at the local level and allocate vaccines according to a dynamic mechanism for updating vulnerability and vaccine uptake.

Results: A novel approach is introduced including (I) Vulnerability data collection (including country-specific data on demographic, socioeconomic, epidemiological, healthcare, and environmental factors), (II) Vaccination prioritization through estimation of a unique Vulnerability Index composed of a range of factors selected and weighed through an Artificial Intelligence (AI-enabled) expert elicitation survey and scientific literature screening, and (III) Values consideration by identification of the most effective GIS-assisted allocation of vaccines at the local level, considering context-specific constraints and objectives.

View Article and Find Full Text PDF

Introduction: Quality of care and physical access to health facilities affect facility choice for family planning (FP). These factors may disproportionately impact young contraceptive users. Understanding which components of service quality drive facility choice among contraceptive users of all ages can inform strategies to strengthen FP programming for all potential users of FP.

View Article and Find Full Text PDF

Introduction: Recent studies suggest that the urban advantage of lower neonatal mortality in urban compared with rural areas may be reversing, but methodological challenges include misclassification of neonatal deaths and stillbirths, and oversimplification of the variation in urban environments. We address these challenges and assess the association between urban residence and neonatal/perinatal mortality in Tanzania.

Methods: The Tanzania Demographic and Health Survey (DHS) 2015-2016 was used to assess birth outcomes for 8915 pregnancies among 6156 women of reproductive age, by urban or rural categorisation in the DHS and based on satellite imagery.

View Article and Find Full Text PDF

Background: Understanding the availability of rapid diagnostic tests (RDTs) is essential for attaining universal health care and reducing health inequalities. Although routine data helps measure RDT coverage and health access gaps, many healthcare facilities fail to report their monthly diagnostic test data to routine health systems, impacting routine data quality. This study sought to understand whether non-reporting by facilities is due to a lack of diagnostic and/or service provision capacity by triangulating routine and health service assessment survey data in Kenya.

View Article and Find Full Text PDF

Subnational projections of under-5 mortality (U5M) have increasingly become an essential planning tool to support Sustainable Development Goals (SDGs) agenda and strategies for improving child survival. To support child health policy, planning, and tracking child development goals in Kenya, we projected U5M at units of health decision making. County-specific annual U5M were estimated using a multivariable Bayesian space-time hierarchical model based on intervention coverage from four alternate intervention scale-up scenarios assuming 1) the highest subnational intervention coverage in 2014, 2) projected coverage based on the fastest county-specific rate of change observed in the period between 2003-2014 for each intervention, 3) the projected national coverage based on 2003-2014 trends and 4) the country-specific targets of intervention coverage relative to business as usual (BAU) scenario.

View Article and Find Full Text PDF
Article Synopsis
  • Rhinoviruses (RV) present in humans show a lot of genetic variation, but their behavior in different social environments is not well studied.
  • This research investigated RV dynamics in Kenya by examining genetic sequences from various settings, including households, a school, and health facilities, finding the highest diversity of RV types at the nationwide level.
  • The study underscores the importance of social structures in influencing RV dynamics and suggests that understanding these patterns can improve public health strategies, with future research focusing on whole-genome analysis for deeper insights.
View Article and Find Full Text PDF

Background: Pregnant women in sub-Saharan Africa (SSA) experience the highest levels of maternal mortality and stillbirths due to predominantly avoidable causes. Antenatal care (ANC) can prevent, detect, alleviate, or manage these causes. While eight ANC contacts are now recommended, coverage of the previous minimum of four visits (ANC4+) remains low and inequitable in SSA.

View Article and Find Full Text PDF

Objectives: To achieve universal health coverage, adequate geographic access to quality healthcare services is vital and should be characterized periodically to support planning. However, in Kenya, previous assessments of geographic accessibility have relied on public health facility lists only, assembled several years ago. Here, for the first time we assemble a geocoded list of public and private health facilities in 2021 and make use of this updated list to interrogate geographical accessibility to all health providers.

View Article and Find Full Text PDF

Background: Access to healthcare is imperative to health equity and well-being. Geographic access to healthcare can be modeled using spatial datasets on local context, together with the distribution of existing health facilities and populations. Several population datasets are currently available, but their impact on accessibility analyses is unknown.

View Article and Find Full Text PDF

With the onset of the coronavirus disease 2019 (COVID-19) pandemic, public health measures such as physical distancing were recommended to reduce transmission of the virus causing the disease. However, the same approach in all areas, regardless of context, may lead to measures being of limited effectiveness and having unforeseen negative consequences, such as loss of livelihoods and food insecurity. A prerequisite to planning and implementing effective, context-appropriate measures to slow community transmission is an understanding of any constraints, such as the locations where physical distancing would not be possible.

View Article and Find Full Text PDF

Maternal and perinatal mortality remain huge challenges globally, particularly in low- and middle-income countries (LMICs) where >98% of these deaths occur. Emergency obstetric care (EmOC) provided by skilled health personnel is an evidence-based package of interventions effective in reducing these deaths associated with pregnancy and childbirth. Until recently, pregnant women residing in urban areas have been considered to have good access to care, including EmOC.

View Article and Find Full Text PDF

School-based sampling has been used to inform targeted responses for malaria and neglected tropical diseases. Standard geostatistical methods for mapping disease prevalence use the school location to model spatial correlation, which is questionable since exposure to the disease is more likely to occur in the residential location. In this paper, we propose to overcome the limitations of standard geostatistical methods by introducing a modelling framework that accounts for the uncertainty in the location of the residence of the students.

View Article and Find Full Text PDF