Publications by authors named "Peter M Itsura"
Background: Cervical cancer is one of the leading causes of cancer mortality among women in Kenya due to late presentations, poor access to health care, and limited resources. Across many low- and middle-income countries infrastructure and human resources for cervical cancer management are currently insufficient to meet the high population needs therefore patients are not able to get appropriate treatment.
Objective: This study aimed to describe the clinicopathological characteristics and the treatment profiles of cervical cancer cases seen at Moi Teaching and Referral Hospital (MTRH).
Article Synopsis
- A study was conducted with 39 women in Western Kenya who have HIV and are receiving antiretroviral therapy, focusing on HIV-1 RNA levels in the genital tract.
- The research aimed to measure HIV shedding before and after treatment with cryotherapy for cervical lesions.
- Results showed that most HIV shedding occurred before cryotherapy, indicating that the treatment itself was not the main reason for the shedding.
Background: The main pediatric (0-18 years) gynecologic cancers include stromal carcinomas (juvenile granulosa cell tumors and Sertoli-Leydig cell tumors), genital rhabdomyosarcomas and ovarian germ cell. Outcomes depend on time of diagnosis, stage, tumor type and treatment which can have long-term effects on the reproductive career of these patients. This study seeks to analyze the trends in clinical-pathologic presentation, treatment and outcomes in the cases seen at our facility.
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- The study aimed to evaluate the types of HPV infections in HIV-positive and HIV-negative women in western Kenya who were receiving treatment for cervical abnormalities.
- Researchers conducted a prospective observational study and collected data on HPV types, demographics, and HIV status among 175 participants, using methods like visual inspection and cervical swabs.
- Results showed that HIV-positive women had a higher prevalence of low-risk HPV and more high-risk HPV types, with those needing a more extensive procedure (LEEP) being at an even greater risk for multiple high-risk HPV infections compared to those getting cryotherapy.