Publications by authors named "Peter Kristian Kofoed"

Purpose: To assess retinal perfusion in eyes with unilateral ocular ischaemic syndrome (OIS) and to compare with control subjects.

Methods: Retrospective case series. Linear blood flow velocities in macular vessels were estimated using motion-contrast fundus photography in eight patients with unilateral OIS (eight OIS eyes, seven fellow eyes) and 12 control subjects.

View Article and Find Full Text PDF

Introduction: The aim of this study was to examine the use of quantitative fluorescein angiographic analysis as a means of estimating rates of perfusion of the retina in eyes with a circulatory deficit secondary to carotid artery stenosis.

Material And Methods: The study included 21 eyes with ocular ischaemic syndrome (OIS) and 20 control eyes from subjects with carotid artery stenosis but without signs of ocular ischaemia. Analyses of video fluorescein angiograms extracting time intervals for the time delay between specific phases of the angiogram were performed.

View Article and Find Full Text PDF

Purpose: To examine retinal function in relation to retinal perfusion pressure in patients with carotid artery stenosis.

Methods: Thirteen patients with carotid artery stenosis without clinical eye disease underwent assessment of ophthalmic artery systolic blood pressure (OSP) by ocular pneumoplethysmography, carotid artery obstructive disease by ultrasonography, intraocular pressure by applanation tonometry, retinal perfusion by fluorescein angiography and retinal function by multifocal electroretinography (mfERG). Data analysis compared the eye on the most stenotic side with the fellow eye in the same patient.

View Article and Find Full Text PDF

Purpose: To examine retinal electrophysiological function and retinal thickness in healthy eyes before and after hyperbaric oxygen (HBO) exposure.

Methods: The healthy eye in each of six subjects who underwent experimental HBO treatment for branch retinal vein occlusion in the fellow eye was examined using multifocal electroretinography (mfERG) and optical coherence tomography (OCT) at baseline and following a course of five consecutive daily sessions of exposure to HBO at 2.4 atmospheres of absolute pressure lasting 90 min each.

View Article and Find Full Text PDF

Purpose: To examine dark-adapted retinal function in subjects with type 2 diabetes during transient hyperglycemia.

Methods: Twenty-four subjects with type 2 diabetes and minimal diabetic retinopathy were randomized to an oral glucose tolerance test (OGTT) or a fasting regimen. One study eye was kept in the dark-adapted state at all times.

View Article and Find Full Text PDF

Purpose. To examine retinal function in chronic ocular ischemia using multifocal electroretinography (mfERG). Methods.

View Article and Find Full Text PDF

Purpose: To report the result of ranibizumab administration in an eye with ocular ischaemic syndrome.

Methods: Fluorescein angiography, ocular pneumoplethysmography and retinal vessel calibre measurement.

Results: An 85-year-old man with ocular ischaemic syndrome demonstrated vision loss, retinal vessel calibre constriction and profound retinal ischaemia after intravitreal ranibizumab.

View Article and Find Full Text PDF

Purpose: To study the relation between ambient environmental ultraviolet radiation exposure and lens fluorescence.

Methods: Non-invasive lens fluorometry measurements were compared in healthy Bolivian and Danish subjects. Background ultraviolet radiation was 4.

View Article and Find Full Text PDF

Purpose: To examine variations in retinal vessel diameters during acclimatization of native highlanders to normobaric normoxia at sea level.

Methods: Fifteen healthy residents of the greater La Paz region in Bolivia (3600 m above sea level) were examined thrice over a 72-day period, after having traveled by airplane to Copenhagen, Denmark, near sea level.

Results: In the study subjects, hematocrit decreased from 49.

View Article and Find Full Text PDF

Purpose: To examine variations in retinal electrophysiology assessed by multifocal electroretinogram (mfERG) during acclimatization of native highlanders to normobaric normoxia at sea level.

Methods: Eight healthy residents of the greater La Paz area in Bolivia (3600 m above sea level) were examined over 72 days after arriving in Copenhagen, Denmark (sea level). A control group of eight healthy lowlanders was used for comparison.

View Article and Find Full Text PDF

Introduction: Ultrasonic carotid interna scanning is today the gold standard for diagnosing carotid stenosis in patients with stroke or transient ischemic attack. The procedure of ultrasonic carotid interna scanning is not a well-defined procedure. Knowledge of the reproducibility of the method used in own department is important in order to evaluate its usefulness.

View Article and Find Full Text PDF