: An emerging pathogen and rare cause of wound infection in children.

Background: is an anaerobic gram-positive bacilli first isolated from swine manure in 2003 but has since been associated with human infections.

Methods: We describe a pediatric case of infection following a below-knee amputation for a limb injury and its treatment. Methods of identifying and reported in vitro antimicrobial minimum inhibitory concentrations from the literature are reviewed.

Disseminated histoplasmosis associated with acquired hemophagocytic lymphohistiocytosis.

Hemophagocytic lymphohistiocytosis (HLH) is a potentially life-threatening clinical syndrome caused by uncontrolled activation of lymphocytes and histiocytes resulting in high levels of cytokines. Acquired HLH occurs in autoimmune, inflammatory, infectious, and immunosuppressive disorders. Prompt identification and treatment of an underlying triggering cause improves clinical outcome.

An evaluation of the management of asymptomatic catheter-associated bacteriuria and candiduria at The Ottawa Hospital.

Background: Asymptomatic catheter-associated urinary tract infections (CAUTIs) are common in hospitalized patients. They are associated with a low incidence of sequelae and morbidity, and in most patients resolve spontaneously on removal of the catheter. As a result, it is not recommended that asymptomatic catheter-associated bacteriuria or candiduria be treated with antimicrobial agents while the catheter remains in place because it may lead to the evolution of resistant flora.

Surveillance for hospital outbreaks of invasive group a streptococcal infections in Ontario, Canada, 1992 to 2000.

Background: Streptococcus pyogenes can cause severe disease in the individual patient and dramatic hospital outbreaks.

Objective: To describe the epidemiology of hospital outbreaks of invasive group A streptococcal infection in order to understand the potential benefit of proposed outbreak investigation and management strategies.

Design: Prospective, population-based surveillance.

Severe group a streptococcal soft-tissue infections in Ontario: 1992-1996.

A prospective, population-based, surveillance study of invasive soft-tissue infections due to group A streptococci was conducted in Ontario, Canada, from 1992 through 1996. Demographic and clinical information was obtained by patient interview and chart review. Isolates were characterized by M protein and T agglutination typing.

An unusual cause for granulomatous inflammation of the penis.

We report a highly unusual type of inflammatory reaction secondary to the insertion of needle in the penis with formation of a nodule of 2.1 cm in diameter, histologically mimicking lymphogranuloma venereum.