Survival and function of transplanted islet cells on an in vivo, vascularized tissue engineering platform in the rat: A pilot study.

As in vivo tissue engineering of complex tissues and organs progresses, there is a need for an independently vascularized, alterable, and recoverable model. Current models of islet cell transplantation (release into the portal venous system, placement under the renal capsule, and microencapsulation) lack these qualities. We have developed a model of angiogenesis and spontaneous tissue generation in the rat that lends itself as a potential platform for tissue engineering.

Survival and Function of Transplanted Islet Cells on an in Vivo, Vascularized Tissue Engineering Platform in the Rat: A Pilot Study 1.

As in vivo tissue engineering of complex tissues and organs progresses, there is a need for an independently vascularized, alterable, and recoverable model. Current models of islet cell transplantation (release into the portal venous system, placement under the renal capsule, and microencapsulation) lack these qualities. We have developed a model of angiogenesis and spontaneous tissue generation in the rat that lends itself as a potential platform for tissue engineering.

Free fibula flap-donor-site morbidity: case report and review of the literature.

The free osteocutaneous fibula flap is the most commonly transferred vascularized bone flap used today. The associated donor site morbidity is well-reported, including vague pain which usually presents late, and is associated with few objective clinical findings. The authors report a case in which the pain had an identifiable cause; they suggest how this can be avoided.