Publications by authors named "Peter J Giannoccaro"
Association of Bicuspid aortic valve morphology and aortic root dimensions: a substudy of the aortic stenosis progression observation measuring effects of rosuvastatin (ASTRONOMER) study.
Echocardiography
February 2010
Article Synopsis
- Bicuspid aortic valve (BAV) is a common condition causing aortic stenosis in people under 50, classified into Type I (fusion of right and left cusps) and Type II (fusion of right and non-coronary cusps).
- The study aimed to investigate the relationship between BAV leaflet types and aortic root measurements as part of the ASTRONOMER research project, which examines the effects of rosuvastatin on aortic stenosis progression.
- Results showed that among 89 patients, those with Type I BAV had larger aortic dimensions compared to Type II, suggesting that BAV orientation may influence the severity of aortic root pathology.
Association of mitral annular calcification and aortic valve morphology: a substudy of the aortic stenosis progression observation measuring effects of rosuvastatin (ASTRONOMER) study.
Eur Heart J
June 2008
Aims: Mitral annular calcification (MAC) is characterized by calcium and lipid deposition in the annular fibrosa of the mitral valve. Although individuals with MAC are at increased risk of cardiovascular events, little is known about the significance of this finding in patients with concurrent aortic stenosis (AS). The aim of this study was to describe the association of baseline MAC and aortic valve morphology in asymptomatic patients enrolled in the ASTRONOMER study, a multicentre study to assess the effect of Rosuvastatin on the progression of AS.
View Article and Find Full Text PDFObjective: Although impaired diastolic function is common in aortic stenosis (AS), little is known about the clinical usefulness of tissue Doppler imaging (TDI) to detect diastolic dysfunction in patients with mild to moderate AS. The objective was to describe both conventional and TDI measurements of diastolic function in asymptomatic patients enrolled in the Aortic Stenosis Progression Observation Measuring Effects of Rosuvastatin study, a multicenter study to assess the effect of rosuvastatin on the progression of AS.
Methods: Baseline echocardiography measurements, including left ventricular interventricular septal thickness, posterior wall thickness, cavity dimensions, and ejection fraction were obtained.