Adapting generalized suitability curves from Brown trout to Minnow using 1D and 2D aquatic habitat models.

The article focuses on adapting generalized depth preference and flow velocity characteristics from Brown trout (Salmo trutta morpha fario) to the Minnow (Phoxinus phoxinus). The results obtained were used to model habitat suitability with 1D and 2D models. Since 1995, research on assessing aquatic habitat quality has been ongoing on 77 mountain streams in Slovakia.

Genetic Polymorphisms in Exon 5 and Intron 5 and 7 of Are Associated with Rheumatoid Arthritis Risk in a Hungarian Population.

Background: Rheumatoid arthritis (RA) is chronically persistent synovitis and systemic inflammation. Although multiple contributors are detected, only one is pivotal in the neonatal period: the negative selection of autoimmune naïve T-cells by the autoimmune regulator (AIRE) transcriptional factor.

Methods: Single-nucleotide polymorphisms (SNPs) in the DNA-binding site of may determine its function and expression.

Association Between Polymorphisms rs870881(C>T), rs1003854(T>C) and Rheumatoid Arthritis Risk: A Hungarian Case-control Study.

Background/aim: Autoimmune regulator (AIRE) is a transcription factor that plays pivotal role in controlling autoimmunity. In the thymus, it supports the presentation of peripheral tissue antigens to developing T cells, where recognition of these self-antigens negatively selects the autoimmune naïve T-cells by central tolerance. Studies demonstrated that single-nucleotide polymorphisms (SNPs) in AIRE alter transcription and propagate clonal survival of autoimmune T cells, therefore increase susceptibility to autoimmune diseases.

Effect of HEAT therapy in patiEnts with type 2 Diabetes mellitus (HEATED): protocol for a randomised controlled trial.

Introduction: The burden of type 2 diabetes mellitus (T2DM) is increasing worldwide. Heat therapy has been found effective in improving glycaemic control. However, to date, there is a lack of randomised controlled studies investigating the efficacy of heat therapy in T2DM.

End-range Maitland mobilization decreasing pain sensitivity in knee osteoarthritis: randomized, controlled clinical trial.

Background: Pressure pain threshold (PPT) is a widely applied method for measuring the magnitude of increased peripheral and central pain sensitivity causing hyperalgesia in knee osteoarthritis (OA). Although manual therapy techniques effects positively PPT, the effect of end-range Maitland mobilization has not been evaluated in knee OA.

Aim: The aim of this study was to investigate the effect of end-range Maitland mobilization compared to sham manual therapy technique on PPT and function-related measures.

A New and Validated, Randomised, Controlled Placebo Water Development Trial for Medicinal Water-based Research.

Background/aim: To develop and validate an easy-to-use and cheap method capable of producing placebo from tap water for medicinal water efficacy trials.

Patients And Methods: Patients were divided into two groups, medicinal water and tap water group. A single 20-minute-long treatment was performed in bathtubs.

Urinary orosomucoid: a new marker of cardiovascular risk in psoriatic patients?

Purpose: Psoriasis is one of the most common lifelong lasting dermatologic diseases. According to the latest studies, psoriatic patients have a higher risk of developing cardiovascular diseases. Psoriasis is considered as a systemic inflammatory disease.

[Utilization indicators of balneotherapy in Hungary].

Introduction: The role of spa therapy is well defined and its importance has significantly increased in the healthcare but the utilization indicators of the implemented treatments are less known.

Aim: The objective of our study was to analyze the utilization and the social insurance indicators of the healthcare publicly financed by health insurance in spa institutions.

Data And Methods: The data used for the analysis were derived from the funding database of the National Health Insurance Fund of Hungary.

Transcutaneous Carbon Dioxide Treatment Affects Heart Rate Variability - A Pilot Study.

Background: The aim of this study was to investigate the effects of carbon-dioxide treatment on heart rate variability (HRV) parameters: mean RR interval (RRI), standard deviation of RR intervals (SDNN), root mean square of successive RR differences (RMSSD); and Porta and Guzik indices, as measures of heart rate asymmetry.

Materials And Methods: Twenty patients were enrolled (mean±SD, age=59±7.8 years).

Urinary Orosomucoid A Potential Marker Of Inflammation In Psoriasis.

: Psoriasis is one of the most common chronic, life-long dermatologic diseases, which has considerable negative effects on quality of life. Psoriasis is considered as a systemic inflammatory disease, thus acute phase proteins such as C-reactive protein (CRP) and orosomucoid (ORM) have been shown to play a role in its pathophysiology. This study was aimed to compare CRP, serum ORM (se-ORM) and urinary ORM (u-ORM) levels of psoriatic patients to healthy individuals.

Balneotherapy in Psoriasis Rehabilitation.

Background/aim: This study aimed to report a balneotherapy-based psoriasis rehabilitation protocol and assess its effectivity.

Patients And Methods: Eighty psoriatic patients who underwent a 3-week-long inward balneotherapy-based rehabilitation were enrolled. Psoriasis Area and Severity Index (PASI) score and high sensitivity C-reactive protein (CRP) were determined on admission and before discharge.

Angiotensin-converting Enzyme Inhibition Improves the Effectiveness of Transcutaneous Carbon Dioxide Treatment.

Aim: To study the effect of carbon dioxide (CO) therapy on the nitric oxide (NO) pathway by monitoring plasma asymmetric dimethylarginine (ADMA) concentrations.

Patients And Methods: Forty-seven hypertensive patients who underwent transcutaneous CO therapy were enrolled. Thirty healthy individuals were recruited for the control group.

[Psoriasis and oxidative stress].

Psoriasis is among the most common dermatological diseases worldwide. Its significance is emphasized by adverse effects on quality of life, caused by chronic pain, physical and psychical disability due to psoriatic plaques. Besides the development of psoriatic arthritis, which often causes permanent joint damage, former studies revealed an increased risk of inflammatory bowel disease, cardiovascular disease and certain types of cancer.

New Validated Signal-averaging-based Electrocardiography Method to Determine His-ventricle Interval.

Background/aim: The signal-averaging (SA) technique is used to record high-resolution electrocardiograms (HRECGs) showing cardiac micropotentials. We aimed to develop a non-invasive signal-averaging-based portable bedside device to determine His-ventricle interval.

Patients And Methods: After amplifying the HRECG recordings, signal duration and voltage can be measured up to four decimal precision.

Monitoring of L-Arginine and Endogenous Dimethylarginines in Survivor Septic Patients - A Pilot Study.

Background/aim: Nitric oxide (NO) pathway plays a major role in the development and advancement of inflammation. We aimed to design a study and investigate its feasibility to show the changes of L-arginine, asymmetric dimethylarginine (ADMA) and symmetric dimethylarginine (SDMA), which are important regulators of the NO pathway.

Patients And Methods: Concentrations of L-arginine, ADMA and SDMA were measured by liquid chromatography-tandem mass spectrometry.