Publications by authors named "Peter Hecht"

Article Synopsis
  • More severe forms of atopic dermatitis and psoriasis significantly impact quality of life, lead to higher healthcare costs, and are linked to other health issues; addressing these problems early can help lessen the burden.
  • The BIOMAP consortium is a large-scale research initiative that compiles clinical and molecular data from various studies to improve the understanding of disease severity and identify reliable biomarkers.
  • The consortium emphasizes the importance of using consistent definitions for disease severity and considers various factors when analyzing data to ensure that findings are relevant to both patients and healthcare practitioners.
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Pancreatic β cell failure is key to type 2 diabetes (T2D) onset and progression. Here, we assess whether human β cell dysfunction induced by metabolic stress is reversible, evaluate the molecular pathways underlying persistent or transient damage, and explore the relationships with T2D islet traits. Twenty-six islet preparations are exposed to several lipotoxic/glucotoxic conditions, some of which impair insulin release, depending on stressor type, concentration, and combination.

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Driver distraction is a major cause of traffic accidents, with mobile telephones as a key source of distraction. In two studies, we examined distraction of pedestrians associated with mobile phone use. The first had 60 participants walk along a prescribed route, with half of them conversing on a mobile phone, and the other half holding the phone awaiting a potential call, which never came.

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