Publications by authors named "Peter Gordon Morris"
Article Synopsis
- T₂*-weighted MRI at 7 T can differentiate between multiple sclerosis lesions and benign white-matter lesions based on the visibility of central blood vessels.
- This study aims to enhance the imaging technique's sensitivity to small veins at both 3 T and 7 T by optimizing scanning parameters and using signal-to-noise ratio measurements and simulations.
- Results indicate that optimized imaging improves the detection of veins in lesions in multiple sclerosis patients, highlighting the advantages of using ultra-high-field MRI.
Functional magnetic resonance imaging (fMRI) is increasingly being used for animal studies studying the transmission of nociceptive information. Application of noxious mechanical stimuli is widely used for animal and human assessment of pain processing. Any accessory hardware used in animal imaging studies must, however, be sufficiently small to fit in the magnet bore diameter and be non-magnetic.
View Article and Find Full Text PDFFunctional magnetic resonance imaging (fMRI) of blood oxygen level dependent (BOLD) haemodynamic responses was used to study the effects of the noxious substance capsaicin on whole brain activation in isofluorane anaesthetised rats. Rats (n=8) received intradermal injection of capsaicin (30 microg/5 microl), or topical cream (0.1%) capsaicin and BOLD responses were acquired for up to 120 min.
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