Publications by authors named "Peter Gawthorpe"
Cancers (Basel)
January 2021
Article Synopsis
- International guidelines for diagnosing Lynch syndrome recommend molecular screening for colorectal cancers but need updates due to advancements in understanding and technology.
- Current guidelines primarily focus on colorectal cancers, missing a significant number of Lynch-spectrum tumors, especially in men and women with Lynch syndrome, which calls for broader screening approaches.
- New technologies allow for testing beyond tumor tissue, suggesting potential for earlier diagnosis in Lynch syndrome cases through methods like assessing non-cancerous tissues for microsatellite instability or MMR deficiency.
