Correction: Cu(i) diimine complexes as immobilised antibacterial photosensitisers operating in water under visible light.

[This corrects the article DOI: 10.1039/D0MA00642D.].

Exploring smooth muscle phenotype and function in a bioreactor model of abdominal aortic aneurysm.

Background: Vascular smooth muscle cells (SMC) are central to arterial structure and function yet their involvement in the progression of abdominal aortic aneurysm (AAA) disease is not well studied. The progressive and silent nature of AAA in man essentially restricts research to the use of "end-stage" tissue recovered during surgical repair. This study aimed to generate an ex vivo model of AAA using protease-treated porcine carotid arteries maintained in a novel bioreactor, and to compare the structural and functional changes in SMC cultured from the recovered vessels with those from human tissue acquired at elective surgical repair.

The circumferential loading of a direct cardiac compression assist device.

Heart disease is the developed world's largest killer. Transplantation of the failing heart remains the most effective treatment currently employed, but demand far exceeds donor supply. In a bid to address this imbalance, the use of mechanical circulatory support has been explored since the mid-1960s.

Amplitude modulation drive to rectangular-plate linear ultrasonic motors with vibrators dimensions 8 mm x 2.16 mm X 1 mm.

In this paper, to exploit the contribution from not only the stators but also from other parts of miniature ultrasonic motors, an amplitude modulation drive is proposed to drive a miniature linear ultrasonic motor consisting of two rectangular piezoelectric ceramic plates. Using finite-element software, the first longitudinal and second lateral-bending frequencies of the vibrator are shown to be very close when its dimensions are 8 mm x 2.16 mm x 1 mm.

The effects of time varying curvature on species transport in coronary arteries.

Alterations in mass transport patterns of low-density lipoproteins (LDL) and oxygen are known to cause atherosclerosis in larger arteries. We hypothesise that the species transport processes in coronary arteries may be affected by their physiological motion, a factor which has not been considered widely in mass transfer studies. Hence, we numerically simulated the mass transport of LDL and oxygen in an idealized moving coronary artery model under both steady and pulsatile flow conditions.

Performance improvement of rectangular-plate linear ultrasonic motors using dual-frequency drive.

To improve the performances of a rectangular-plate linear ultrasonic motor for specific applications, a dual-frequency drive has been proposed and investigated. Through careful design of the rectangular piezoelectric ceramic plate, its first longitudinal resonant frequency coincides with its second lateral bending resonant frequency and is one-third of its higher lateral bending resonant frequency. When a square-wave voltage is used to drive the motor, its first longitudinal and second bending and the higher bending vibration modes are excited.

Disturbed flow promotes deposition of leucocytes from flowing whole blood in a model of a damaged vessel wall.

Departure from simple laminar flow in arteries may promote the local attachment of leucocytes either to intact endothelium or platelet thrombi. We perfused blood through a chamber with a backward facing step, to observe whether adhesion from whole blood to P-selectin was indeed localized to a region of recirculating flow, and whether platelets binding to collagen in such a region could capture leucocytes. Blood flowing over the step established a stable vortex, a reattachment point where forward and backward flow separated, and a simple laminar flow with wall shear rate c.

Quantification of pulmonary autograft characteristics using magnetic resonance imaging.

Background And Aim Of The Study: The diameters and distensibility of the native pulmonary root and their effect on pulmonary autograft performance were examined pre- and postoperatively using cardiac ultrasound and magnetic resonance imaging (MRI).

Methods: Eight patients undergoing the Ross procedure were prospectively involved. The diameters of the native aortic, native pulmonary and autograft roots were measured at the level of the annulus, sinus, sinotubular junction and in the main root using MRI through the cardiac cycle.

The quantification of pulmonary valve haemodynamics using MRI.

The optimum slice location within the pulmonary root to quantify pulmonary valve haemodynamics was examined using magnetic resonance (MR) phase velocity mapping. MRI was carried out on 15 patients with congenital aortic valve disease. Although the patients had aortic valve disease, all measurements were made on the pulmonary valve.

Hydrodynamic function of the second-generation mitroflow pericardial bioprosthesis.

Background: The hydrodynamic function of the smaller size Mitroflow Synergy stented pericardial bioprostheses has been studied in an in vitro fresh tissue aortic root model and compared with previous studies of free-sewn bioprostheses.

Methods: Three valves of each of the sizes 19, 21, and 23 mm were sutured into fresh tissue aortic roots and tested in a pulsatile flow simulator using two different ventricular input impedance conditions. A high-speed camera was used to study the leaflet opening and closing configurations.