Dual action electrochemical bandage operated by a programmable multimodal wearable potentiostat.

We have developed electrochemical bandage (e-bandage) prototypes that generate the reactive oxygen species hypochlorous acid (HOCl) or hydrogen peroxide (HO) for potential use to treat biofilm-infected wounds in humans. We have shown that both e-bandage-generated HOCl and HO kill biofilms in vitro and in infected wounds on mice, with the former being more active in vitro. The HO-generating e-bandage, more so than the HOCl-generating e-bandage, was associated with improved healing of infected wounds.

DUAL ACTION ELECTROCHEMICAL BANDAGE OPERATED by a PROGRAMMABLE MULTIMODAL WEARABLE POTENTIOSTAT.

Electrochemical bandages (e-bandages) can be applied to biofilm-infected wounds to generate reactive oxygen species, such as hypochlorous acid (HOCl) or hydrogen peroxide (H O ). The e-bandage-generated HOCl or H O kills biofilms and in infected wounds on mice. The HOCl-generating e-bandage is more active against biofilms , although this distinction is less apparent .

Thermodynamic Evidence of Structural Transformations in CO-Loaded Metal-Organic Framework Zn(MeIm) from Heat Capacity Measurements.

Metal-organic frameworks are a class of porous compounds with potential applications in molecular sieving, gas sequestration, and catalysis. One family of MOFs, zeolitic imidizolate frameworks (ZIFs), is of particular interest for carbon dioxide sequestration. We have previously reported the heat capacity of the sodalite topology of the zinc 2-methylimidazolate framework (ZIF-8), and in this Article we present the first low-temperature heat capacity measurements of ZIF-8 with various amounts of sorbed CO.