Aim: To determine the frequency of small bowel ulcerative lesions in patients with peptic ulcer and define the significance of those lesions.
Methods: In our prospective study, 60 consecutive elderly patients with upper gastrointestinal bleeding from a peptic ulceration (cases) and 60 matched patients with a non-bleeding peptic ulcer (controls) underwent small bowel capsule endoscopy, after a negative colonoscopy (compulsory in our institution). Controls were evaluated for non-bleeding indications.
World J Gastrointest Pharmacol Ther
February 2014
The incidence of esophageal adenocarcinoma, a poor prognosis neoplasia, has risen dramatically in recent decades. Barrett's esophagus represents the best-known risk factor for esophageal adenocarcinoma development. Non-steroidal anti-inflammatory drugs through cyclooxygenase-2 inhibition and prostaglandin metabolism regulation could control cell proliferation, increase cell apoptosis and regulate the expression of growth and angiogenic factors.
View Article and Find Full Text PDFBackground/aims: Duodenogastric reflux is a possible risk factor for esophageal adenocarcinoma (CA) development. Gastric surgery that destroys or distorts the pylorus is a good model to study the effects of duodenogastric reflux. To define the consequences of gastrectomy in patients with Barrett esophagus (BE).
View Article and Find Full Text PDFDoctors and other health professionals should always offer information to patients about the risks, benefits and alternatives to the treatment or examination proposed. Such information should be offered in a timely fashion and in a form understandable to the patient. The professional should assess the patients' ability to comprehend and to make a judgement if their consent is to be valid.
View Article and Find Full Text PDF