Pro-inflammatory cytokines expression increases following low- and high-magnitude cyclic loading of lumbar ligaments.

Repetitive or overuse disorders of the lumbar spine affect the lives of workers and athletes. We hypothesize that repetitive anterior lumbar flexion-extension under low or high load will result in significantly elevated pro-inflammatory cytokines expression several hours post-activity. High loads will exhibit significantly higher expression than low loads.

Neuromuscular disorder in response to anterior cruciate ligament creep.

Objective: To determine the effect of creep developed in the anterior cruciate ligament and other viscoelastic knee structures on the function of the flexor and extensor muscles of males and females.

Design: Static load applied to the proximal tibia of young healthy male and female subjects in a laboratory setting with maximal voluntary knee flexion and extension performed before and after the load application.

Background: Static loads applied to various joints during occupational and sports activities are epidemiologically linked to higher than normal rates of disability reports.