Publications by authors named "Peter Cw Fung"
Article Synopsis
- EGb761, a standard extract from Ginkgo biloba, contains compounds that protect heart cells from damage caused by low oxygen followed by reoxygenation, and this study investigates its effects on the caspase signaling pathway.
- Cardiomyocyte experiments showed that pretreatment with EGb761 and its key components (quercetin and bilobalide) reduced factors associated with cell death, specifically by preventing the release of cytochrome c and the activation of caspases.
- Quercetin was found to be particularly effective, demonstrating greater protective effects compared to bilobalide, highlighting that the antioxidant properties of EGb761 might target the mitochondria-dependent caspase pathway to mitigate heart injury.
