Publications by authors named "Peter Bradtke"
Article Synopsis
- Drug-based antiretroviral therapies (ART) effectively control HIV replication but can't eliminate the virus since it remains as integrated proviral reservoirs in cells.
- Genome editing tools like the HIV-1 LTR-specific designer-recombinase Brec1 show promise in removing these integrated HIV genomes, indicating potential for curative therapies.
- A comprehensive preclinical study of Brec1 demonstrated it has minimal safety risks, including no harmful immune responses, making it a suitable candidate for future clinical trials aimed at eradicating HIV-1.
Article Synopsis
- * Researchers created mice with active IL-6R in T cells to study its effects, finding that it led to lung inflammation and activated T cell accumulation, particularly TH17 cells.
- * While gp130 signaling in T cells promotes activated T cell presence and memory formation, it does not directly cause TH17 differentiation or lead to T cell lymphoma.
Kidney-resident innate-like memory γδ T cells control chronic infection of mice.
Proc Natl Acad Sci U S A
January 2023
γδ T cells are involved in the control of infection, but their importance in protection compared to other T cells is unclear. We used a mouse model of systemic infection associated with high bacterial load and persistence in the kidney. Infection caused fulminant accumulation of γδ T cells in the kidney.
View Article and Find Full Text PDFResearchers have examined factors of authors such as sex of author, gender identity, and seniority within the field of behavior analysis to determine if any biases towards a certain group existed. Most recently, Kranak et al. (2020) found that women and new authors are well-represented in the Journal of Applied Behavior Analysis (JABA).
View Article and Find Full Text PDFThe Journal of Applied Behavior Analysis (JABA) is considered the flagship journal for the discipline of applied behavior analysis. Thus, popular research topics and other publication trends within JABA reflect the current cultural and scientific contingencies governing the field of behavior analysis. Researchers have previously quantified a number of authorship trends in JABA (and other behavior-analytic journals) across a number of variables, such as gender identity and sex of author, country of origin, or seniority within the field (Dunlap et al.
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