Publications by authors named "Peter Bjarn Christensen"
Article Synopsis
- Replication stress from a deficiency leads to mitochondrial dysfunction and metabolic stress, causing significant changes in metabolites.
- Supplementation with NAD and its precursor, nicotinamide riboside (NR), can restore autophagy and improve mitochondrial morphology in mouse embryonic fibroblasts (MEFs).
- However, while NR supplementation helps MEFs, it does not protect nematodes from oxidative stress caused by the deficiency, indicating variability in intervention effectiveness depending on the organism.
