Effect of finger ulnar deviation on gliding resistance of the flexor digitorum profundus tendon within the A1 and A2 pulley complex.

Purpose: To evaluate the effect of ulnar deviation of the finger on gliding resistance of the flexor digitorum profundus tendon within the A1 and A2 pulley complex.

Methods: Thirty-two human cadaveric fingers (index through small fingers) were used. The gliding resistance was measured at 5 different angles of ulnar deviation (0 degrees, 15 degrees, 30 degrees, 45 degrees, 60 degrees).

Flexor digitorum profundus tendon tension during finger manipulation.

Abstract The purpose of this study was to measure the tension in the flexor digitorum profundus (FDP) tendon in zone II and the digit angle during joint manipulations that replicate rehabilitation protocols. Eight FDP tendons from eight human cadavers were used in this study. The dynamic tension in zone II of the tendon and metacarpophalangeal (MCP) joint angle were measured in various wrist and digit positions.

Short-term assessment of optimal timing for postoperative rehabilitation after flexor digitorum profundus tendon repair in a canine model.

Abstract The purpose of this study was to compare the short-term outcome following flexor tendon repair for postoperative rehabilitation commencing on day 1 (a common clinical choice) versus day 5 (the day on which, with postoperative immobilization, the initial gliding resistance is least in this model) in an in vivo canine model. Work of flexion (WOF) and tendon strength were evaluated following tendon laceration and repair in 24 dogs sacrificed 10 days postoperatively. Starting postoperative mobilization at day 5 resulted in no tendon ruptures compared with tendon ruptures in four of the dogs (33%) in the group subjected to mobilization starting at day 1.

Total and intrasynovial work of flexion of human cadaver flexor digitorum profundus tendons after modified Kessler and MGH repair techniques.

Purpose: The purpose of this study was to compare directly the total work of flexion (TWOF) and the intrasynovial work of flexion (IWOF) of human flexor digitorum profundus tendons and to analyze the ratio of the IWOF to the TWOF of human flexor digitorum profundus tendons. These factors may be important clinically in understanding the role of different methods of postoperative tendon rehabilitation for different types of tendon repairs, especially at the early stage after tendon repair.

Methods: Two different tendon repairs, the modified Kessler and the Massachusetts General Hospital, were used in 18 digits from 6 freshly frozen human cadaver hands.

Immunolocalization of collagen types in the subsynovial connective tissue within the carpal tunnel in humans.

The tenosynovium within the carpal tunnel consists of a single layer of synovial cells, which lines the bursae within the carpal tunnel, and the subsynovial connective tissue (SSCT), which contains the tendon vasculature and other structural elements. In this study, we used immunogold labeling to localize collagen types within the SSCT in three cadaver specimens and three patients with carpal tunnel syndrome. Positive labeling for collagen types I, III and VI was found with immunoelectron microscopy.

Friction of the gliding surface. Implications for tendon surgery and rehabilitation.

Finger flexor tendon rehabilitation has come a long way, but further advances are possible. Ideally, a healing tendon should move, but under the minimum load necessary to achieve motion. It is possible to design suture repairs that minimize the friction between tendon and sheath while simultaneously maintaining adequate strength to provide a wide margin of safety during therapy.

Effect of elbow position on canine flexor digitorum profundus tendon tension.

Tendon injury in the finger remains a clinical challenge to hand surgeons. A canine model is commonly used to study biological effects of tendon injuries and their treatment. There is an important anatomical difference between human and canine anatomy that may be overlooked, however, namely that most of the flexor digitorum profundus (FDP) muscle in dogs takes its origin from the medial epicondyle of the humerus, whereas in humans this muscle arises purely from the forearm.

Gliding resistance of the extensor pollicis brevis tendon and abductor pollicis longus tendon within the first dorsal compartment in fixed wrist positions.

Purpose: While the etiology of de Quervain's disease is unknown, repetitive motion coupled with awkward wrist position and septation within the first dorsal compartment are considered causative factors. We hypothesize that these conditions might produce high gliding resistance, which could then induce micro-damage of the tendons and retinaculum. The purpose of this study was to measure the gliding resistance of the extensor pollicis brevis and abductor pollicis longus tendons within the first dorsal compartment in a human cadaver model.

Epithelioid sarcoma of the hand.

Twenty-eight patients were treated for a primary epithelioid sarcoma of the hand. Twenty-seven patients (96%) had excisions before evaluation, including 11 (39%) with multiple prior excisions with varying diagnoses before epithelioid sarcoma, and all had surgical treatment after referral. The patients' surgical management included three patients with amputation at the forearm, three patients with wide excision, and 21 patients with a partial amputation of the hand.

Finkelstein's test: a biomechanical analysis.

Purpose: Finkelstein's test is the classic diagnostic test for de Quervain's disease. Finkelstein hypothesized that the entry of the muscle bellies of the extensor pollicis brevis (EPB) and abductor pollicis longus (APL) tendons into the first extensor compartment was responsible for the findings observed in his now eponymous test. We agree with Finkelstein's hypothesis and further hypothesize that this position would induce measurable bulk (muscle mass within the retinaculum) and tethering (stretching of synovial tissue) effects within the compartment.

Effect of gap size on gliding resistance after flexor tendon repair.

Background: Gap formation is a common complication after flexor tendon repair and is associated with adhesion formation, tendon rupture, and decreased strength. The purpose of this study was to investigate the effect of gap formation on tendon gliding resistance after flexor tendon repair in a human cadaver model.

Methods: Twelve index, middle, and ring fingers from four adult human cadaveric hands were used.

Vascular pathologic changes in the flexor tenosynovium (subsynovial connective tissue) in idiopathic carpal tunnel syndrome.

We used the Verhoeff-van Gieson stain method to identify histopathology and to localize elastin in the subsynovial connective tissue of the tendon sheath (SSCT) of the middle finger flexor digitorum superficialis (FDS) within the carpal tunnel in 10 carpal tunnel syndrome (CTS) patients and 10 control cadaver specimens. Normal SSCT stained for elastin abundantly around blood vessels and within vessel walls. The typical pathologic findings of CTS patients SSCT included vascular proliferation, vascular hypertrophy, and vascular obstruction with wall thickening.

The effect of partial A2 pulley excision on gliding resistance and pulley strength in vitro.

Purpose: The purpose of this study was to investigate the effect of partial excision of the A2 pulley on the gliding resistance and the strength of the residual pulleys in a human in vitro model with or without tendon repair.

Methods: We used 32 cadaveric human fingers from 11 cadavers. The A2 pulley was excised successively 25%, 50%, and 75%, cutting either from the distal toward the proximal edge or from the proximal toward the distal edge.

Expression of growth factors in canine flexor tendon after laceration in vivo.

Growth factors, transforming growth factor beta (TGF-beta), epidermal growth factor (EGF), platelet-derived growth factor (PDGF), insulin-like growth factor (IGF), basic fibroblast growth factor (bFGF), and vascular endothelial growth factor (VEGF), are critical components of the cutaneous wound healing process. Little is known, however, about the expression of these growth factors in normal flexor tendon healing. In this study, we wished to examine which of these growth factors are present at 10 days following tendon injury in a canine flexor tendon repair model.

Reducing friction by chemically modifying the surface of extrasynovial tendon grafts.

In this study we evaluated methods to reduce the friction of an extrasynovial tendon under a pulley in vitro. The surface of canine peroneus longus (PL) tendons was modified with gelatin and/or hyaluronic acid (HA) under different conditions. The gliding resistance between treated or control tendons and the canine digital flexor pulley was measured during 500 cycles of simulated flexion/extension.

A histological and immunohistochemical study of the subsynovial connective tissue in idiopathic carpal tunnel syndrome.

Background: The most common histological finding in carpal tunnel syndrome is noninflammatory synovial fibrosis. The accumulated effect of minor injuries is believed to be an important etiologic factor in some cases of carpal tunnel syndrome. We sought evidence of such injuries in the synovial tissue of patients with carpal tunnel syndrome and in cadaver controls.

Measurement of gliding resistance of the extensor pollicis longus and extensor digitorum communis II tendons within the extensor retinaculum.

Purpose: The etiology of spontaneous extensor pollicis longus (EPL) tendon rupture is still largely unknown. It is possible that friction within the sheath may play a role. The purposes of this study were to compare gliding resistance of the EPL tendon with that of the extensor digitorum communis tendon of the index finger (EDC II) and to find the wrist position that gives the EPL tendon the lowest gliding resistance.

A prospective clinical practice intervention to improve osteoporosis management following distal forearm fracture.

Secondary prevention of osteoporosis after fracture is underutilized, despite cost-effective therapies. This clinical practice intervention aimed to improve osteoporosis care of the postfracture patient. Residents of Olmsted County, Minnesota, USA, > or = age 45 who sustained a moderate trauma distal forearm fracture were identified, and participants received educational materials, referral for bone densitometry and physician consultation to address osteoporosis in January 1999 through October 2000.

Digital resistance and tendon strength during the first week after flexor digitorum profundus tendon repair in a canine model in vivo.

Background: After flexor tendon repair, the strength of the repair and the resistance to digital motion are important considerations in deciding when to initiate postoperative rehabilitation. Our objective was to assess these factors in a short-term in vivo canine model of flexor tendon repair.

Methods: Forty-eight dogs were randomly allocated to four groups based on the duration of postoperative follow-up (one, three, five, or seven days).

Gliding characteristics and gap formation for locking and grasping tendon repairs: a biomechanical study in a human cadaver model.

Purpose: The purpose of this study was to compare the frictional characteristics and mechanical properties of various locking and grasping suture techniques in a human in vitro model of flexor tendon repair.

Methods: Forty-five cadaveric human flexor digitorum profundus tendons were transected in zone II and repaired using 1 of 5 core suture methods (n = 9 per group): either grasping (modified grasping Kessler, modified Lee) or locking (Pennington, modified Pennington, locking Lee) loop suture techniques. All repairs used 4-0 Supramid looped core suture and an epitenon running suture of 6-0 nylon.