Alkaline pH in intracranial tuberculomas: A Phosphorus magnetic resonance spectroscopy study.

Objectives: Intracranial tuberculomas are one of the common causes of space-occupying lesions of the brain in developing countries. Proton (H) magnetic resonance spectroscopy (MRS) has shown lipid peak in intracranial tuberculomas as a characteristic feature. Phosphorus (P) MRS has been used to evaluate intracranial lesions and to calculate tissue pH non-invasively.

Altered processing of visual memory in patients with mesial temporal sclerosis: an FMRI study.

Introduction: Hippocampal complex and neocortex play distinct, complementary roles in processing of memory, which is impaired in patients with mesial temporal sclerosis (MTS).

Method: Ten right-sided MTS patients and 10 controls were prospectively assessed by functional Magnetic Resonance Imaging (fMRI) using encoding and retrieval of visual memory tasks. Image analyses were done using SPM2 and voxels showing activity with T-score>4 were considered significant.

Developmental reflexes and 31P Magnetic Resonance Spectroscopy of basal ganglia in antipsychotic-naive schizophrenia.

The study examined the high energy-phosphate metabolism of basal ganglia in antipsychotic-naive schizophrenia patients with and without developmental reflexes in comparison to healthy subjects. Nineteen antipsychotic-naive schizophrenics of whom 11 had developmental reflexes and 26 age-sex-matched healthy subjects without developmental reflexes underwent in-vivo 2-D 31P Magnetic Resonance Spectroscopy of basal ganglia on a 1.5-T scanner.

Optimized voxel-based morphometry of gray matter volume in first-episode, antipsychotic-naive schizophrenia.

This study examined gray matter (GM) volume abnormalities in first-episode, antipsychotic-naïve Indian schizophrenia patients. Magnetic resonance images of 18 schizophrenia patients and 18 matched healthy comparison subjects were analyzed by optimized voxel-based morphometry. Schizophrenia patients had significantly smaller global GM and greater global CSF volumes and smaller regional GM volume in superior frontal, inferior frontal, cingulate, post-central, superior temporal and parahippocampal gyri, inferior parietal lobule, insula, caudate nuclei, thalamus and cerebellum.

Pyruvate: an in vivo marker of cestodal infestation of the human brain on proton MR spectroscopy.

Purpose: To study intracranial cestodal cysts using in vivo proton magnetic resonance spectroscopy ((1)H MRS) in an effort to identify metabolite(s) that may help in recognizing the parasitic etiology and, perhaps, viability of such tapeworm cysts. Cestodal infestations of the human central nervous system (CNS)-cysticercosis and hydatidosis-are not rare. Identification of a scolex is considered diagnostic of cysticercosis on imaging.