Tropical Bovine Theileriosis, caused by the protozoan parasite Theileria annulata, poses a significant threat to cattle populations. Currently, Buparvaquone is the sole effective naphthoquinone drug commercially available for its treatment. In our research, we delved into the potential of naturally occurring quinones as alternative treatments.
View Article and Find Full Text PDFUnlabelled: Phytochemical compounds, plumbagin and thymol were evaluated for their efficacy against using MTT cell viability assay. Plumbagin and thymol were found to be effective in preventing the proliferation of infected bovine lymphocytes. The IC values of plumbagin and thymol were 0.
View Article and Find Full Text PDFNon-alcoholic fatty liver disease (NAFLD) is one of the most frequent, chronic liver diseases worldwide and currently has no specific therapy. Our previous study indicated the anti-NAFLD effect of Macrocybe gigantea (Massee) Pegler & Lodge in high-fat diet-fed animals. This study aimed to isolate and identify the active hepatoprotective constituents from M.
View Article and Find Full Text PDFNon-alcoholic Fatty Liver Disease (NAFLD) is one of the growing epidemics of the globe. This study was aimed to evaluate the anti-NAFLD effect of selected IAN derivatives using in silico, in vitro and in vivo models. In silico tools viz.
View Article and Find Full Text PDFExp Parasitol
September 2019
The present study was aimed to check the mosquitocidal activity of tiliamosine isolated from Tiliacora acuminata (Lam.) Hook. f.
View Article and Find Full Text PDFDifferent concentrations of standardized ethanolic extract from the basidiocarps of Tricholoma giganteum Massee (TgEtOH) were screened for hepatoprotective effects in an animal model of rats with nonalcoholic fatty liver disease (NAFLD) fed a high-fat and high-fructose diet. After 4 weeks of treatment with TgEtOH, the relative liver weights, serum lipid concentrations, and biochemical profiles were found to be normal in treated animals compared with those given a standard drug. The macroscopic and histopathological studies clearly indicated that 200 mg/kg of ethanolic extract was effective in ameliorating the abnormalities of NAFLD.
View Article and Find Full Text PDFAegle marmelos Correa., (Rutaceae) is a medium sized tree distributed in South East Asia and used traditionally for the management of obestiy and diabetes. In this study the lipolytic and antiadipogenic effects of (3,3-dimethylallyl) halfordinol (Hfn) isolated from leaves of A.
View Article and Find Full Text PDFContext: Chronic liver disease has become a global health problem. The research for prominent herbal agents for the management of liver diseases is widely increased.
Objective: The root of Abelmoschus esculentus (Linn.
Rheumatoid arthritis is a chronic, progressive and systemic inflammatory disorder mainly affecting the synovial joints. In the present study, we evaluated the anti-arthritic effect of the methanol extract of Saraca asoca (Roxb.) Wilde.
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