Fetal cardiovascular hemodynamics in type 1 diabetic pregnancies at near-term gestation.

Introduction: Poor glycemic control in maternal type 1 diabetes mellitus during pregnancy can affect fetal cardiac and placental function. However, studies concerning fetal central hemodynamics have revealed conflicting results. We hypothesized that in pregnancies complicated by maternal type 1 diabetes, fetal cardiovascular and placental hemodynamics are comparable to the control fetuses at near-term gestation.

How young adults with autism spectrum disorder watch and interpret pragmatically complex scenes.

The aim of the current study was to investigate subtle characteristics of social perception and interpretation in high-functioning individuals with autism spectrum disorders (ASDs), and to study the relation between watching and interpreting. As a novelty, we used an approach that combined moment-by-moment eye tracking and verbal assessment. Sixteen young adults with ASD and 16 neurotypical control participants watched a video depicting a complex communication situation while their eye movements were tracked.

Ascites in newborns - a diagnostic challenge.

Isolated fetal ascites is a rare finding in prenatal ultrasound examination. The finding is always aberrant and requires further exploration. More than half of fetal ascites findings are associated with structural anomalies.

Diagnosis and treatment of severe hemolytic disease of the fetus and newborn: a 10-year nationwide retrospective study.

Objective: Outcome after intrauterine transfusions due to severe hemolytic disease of the fetus and newborn.

Design: Nationwide population-based retrospective cohort study.

Setting: All women treated with intrauterine transfusions for hemolytic disease of the fetus and newborn in Finland in 2003-2012.

Emotions in freely varying and mono-pitched vowels, acoustic and EGG analyses.

Vocal emotions are expressed either by speech or singing. The difference is that in singing the pitch is predetermined while in speech it may vary freely. It was of interest to study whether there were voice quality differences between freely varying and mono-pitched vowels expressed by professional actors.

[Fetal arrhythmias].

The majority of referrals for fetal arrhythmias represent benign atrial premature beats. However, a small number of fetuses might have life-threatening conditions associated with bradycardia or tachycardia. Fetal echocardiography is essential to establish the diagnosis.

Ursodeoxycholic acid in the treatment of intrahepatic cholestasis of pregnancy: a randomized controlled trial.

Purpose: To test the efficacy and safety of ursodeoxycholic acid (UDCA) in the treatment of patients with intrahepatic cholestasis of pregnancy (ICP).

Methods: In the randomized (double-blind, placebo-controlled) study 20 pregnant women with ICP received (random allocation of) either 450 mg/day UDCA or placebo for 14 days during the third trimester of pregnancy. The severity of pruritus was registered and itching scores were assessed before the treatment and weekly thereafter.

Influence of the intentional voice quality on the impression of female speaker.

This study examines the relationship of voice quality and speech-based personality assessment of Finnish-speaking female speakers. Five Finnish-speaking female subjects recorded a text passage with eight different vocal qualities. Samples that passed the preselection test for the voice qualities were played to 50 Finnish-speaking listeners, who reported speaker impressions on a scale of 18 opposite trait pairs.

Vowel formants from the wave equation.

This article describes modal analysis of acoustic waves in the human vocal tract while the subject is pronouncing [o]. The model used is the wave equation in three dimensions, together with physically relevant boundary conditions. The geometry is reconstructed from anatomical MRI data obtained by other researchers.

Antenatal Doppler measurements and early brain injury in very low birth weight infants.

Objective: To determine the correlation between fetoplacental blood flow and brain injury and volumes in very low birth weight (VLBW) infants.

Study Design: Antenatal blood flow from the umbilical artery (UA), middle cerebral artery (MCA), and descending aorta was determined in 70 VLBW infants. The directions of the total diastolic flow of the aortic isthmus and the end-diastolic flow of ductus venosus also were measured.

Pharmacokinetics of fluoxetine and norfluoxetine in pregnancy and lactation.

Background: The aim of this prospective clinical trial was to investigate the pharmacokinetics of fluoxetine and its active metabolite, norfluoxetine, during pregnancy, delivery, and lactation in mothers and their infants.

Methods: Eleven mothers taking fluoxetine and their infants were enrolled in the study. A control group of 10 women who were not taking psychotropic medication were prospectively matched for confounding obstetric characteristics at the time of delivery.