Publications by authors named "Persichetti P"

The proliferation of unlicensed aesthetic medical (UAE) practices in China's plastic surgery industry highlights a pressing global concern, amplified by the growing "beauty economy." Social media platforms perpetuate unattainable beauty standards through edited images and curated pre- and post-operative photos, fueling demand for aesthetic treatments and exacerbating body dysmorphic disorder (BDD). Vulnerable individuals targeted by manipulative advertising often fall victim to unsafe UAE services.

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Introduction: Soft-tissue sarcomas arising in the thigh may require total or subtotal compartmentectomy, with subsequent need for functional reconstruction with free functional muscle transfer (FFMT). We present our series, describing a new approach with chimeric propeller antero-lateral thigh-vastus lateralis (ALT-VL) free flap, which allows for independent muscle inset and soft tissue defect resurfacing.

Patient And Methods: A retrospective review of a prospectively maintained database was performed, analyzing all patients referred to Fondazione Policlinico Universitario Campus Bio-Medico, Rome, Italy, between 2018 and 2023 for soft-tissue sarcomas of the thigh requiring wide excision and reconstruction with functional ALT-VL.

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Introduction: Renuvion was the first FDA approved helium plasma device utilized for subdermal tissue heating to reduce skin laxity. The purpose of this study was to demonstrate that the use of Renuvion improves the outcomes, skin quality and reduces the edema faster after lipoabdominoplasty.

Materials And Methods: Patients with abdominal skin laxity after a weight loss of at least 20 kg, nonsmokers, without major comorbidities, with a minimum 2-year follow-up and standardized pre- and postoperative photographs were included in this study.

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Background: Evidence-based medicine and patient-reported outcome measures (PROMs) are helpful tools in the wound care field, but few studies correlating quality of life (QoL) changes with objective changes exist.

Objective: To investigate the QoL changes following the shift from primary dressings alone to elastic compression bandages in patients with a new diagnosis of vascular skin ulcer, and to evaluate a possible correlation between objective and subjective changes.

Materials And Methods: This study included 122 patients with a new diagnosis of vascular skin ulcer, who had previously used only primary dressings alone.

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Background: Nontuberculous mycobacteria (NTM) periprosthetic infections after breast augmentation procedures are increasingly common worldwide and should raise suspicion after empirical antimicrobial therapy fails but clinical signs of infection persist. In this case experience, the authors suggest the use of negative pressure wound therapy (NPWT) for NTM-infected wounds to obtain a faster periprosthetic space closure, shorten healing time, and anticipate breast reimplantation.

Case Report: This case report describes the successful application of NPWT to manage wound healing after breast removal in a 60-year-old female who underwent secondary breast augmentation 7 years before.

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Article Synopsis
  • Mild-to-moderate blepharoptosis can negatively impact appearance, with some patients hesitant to pursue surgery; Botulinum neurotoxin A (BoNT-A) injections offer a non-surgical alternative.
  • A study included 49 patients (39 females, 10 males) with various causes of eyelid ptosis, using BoNT-A injections and measuring outcomes through MRD-1 changes and patient questionnaires at multiple intervals.
  • Results showed significant eyelid elevation post-treatment, with most patients experiencing improvement and a high willingness to repeat the procedure, although the effects diminished after 24 weeks.
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Introduction: Striae distensae (SD) appear clinically as parallel striae, lying perpendicular to the tension lines of the skin. SD evolve into two clinical phases, an initial inflammatory phase in which they are called "striae rubrae" (SR) and a chronic phase in which they are called striae albae (SA). This study investigates the synergistic effect of nanofat and platelet-rich plasma (PRP) injections on collagen production in fibroblasts derived from SA (SAF).

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This response addresses the evolving trends in aesthetic medicine as influenced by generational differences, particularly the roles of social media and self-expression. It highlights that Baby Boomers tend to prioritize corrective treatments, while Millennials and Generation Z focus on preventive measures and enhancements. The impact of platforms such as Instagram, YouTube, and TikTok in normalizing aesthetic procedures and shaping body image perceptions is discussed, with an emphasis on the psychological implications of these influences.

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Article Synopsis
  • Periorbital rejuvenation is complex, but the article introduces "Temporal MORE," a modified technique that improves the entire periorbital area prominently.
  • 212 patients underwent this procedure with no major complications and significant increases in patient-reported satisfaction scores from pre-op to post-op.
  • Results show high levels of satisfaction for both patients and independent surgeons, indicating that Temporal MORE is effective, safe, and leads to fast recovery.
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Introduction: The use of free-style and propeller perforator-based flaps has been popularized for the reconstruction of moderate size defects in the trunk and extremities, while their application in the field of abdominal reconstruction is seldom reported. The purpose of this report is to describe the authors experience with the use of pedicled perforator-based flaps in abdominal wall reconstruction, presenting the innovative concept of transition from angiosomal to bi-angiosomal and extra-angiosomal perforator flaps and showing applications of the different flap designs according to the multiple clinical scenarios.

Patients And Methods: A total of 15 patients underwent abdominal wall reconstruction with angiosomal, bi-angiosomal, and extra-angiosomal pedicled perforator-based flaps harvested from the surrounding abdominal subunits for superficial or full thickness defects of the abdominal wall of moderate and large dimensions.

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Article Synopsis
  • * Baby Boomers prefer noninvasive procedures for youthful rejuvenation, while Generation X leans towards natural enhancements influenced by authentic testimonials.
  • * Millennials and Generation Z are heavily impacted by social media, with the former focusing on preventive care and the latter on temporary enhancements, highlighting the importance for industry professionals to understand generational trends.
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Background: Upper Extremity Lymphedema following oncological breast surgery affects not only the patient's physique, but also the patient's psychological sphere. One of the best known PROMs-based questionnaires for investigating the condition is the LYMPH-Q. The study aimed to perform the Italian translation and cultural adaptation of the LYMPH-Q and to assess if, independently from disease evolution, arm sleeve improves QoL in these patients.

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Article Synopsis
  • * Conducted from April 2022 to April 2023, it involved 79 patients who saw significant improvements in eyelid appearance and satisfaction, with no link found between the severity of eyelid skin issues before surgery and satisfaction afterward.
  • * The results highlight the importance of using validated questionnaires like FACE-Q to assess patient experiences, indicating that even minor skin excess might benefit from treatment for better cosmetic outcomes and functional improvements.
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Article Synopsis
  • Diastasis recti abdominis (DRA) is an abnormal separation of abdominal muscles linked to issues like back pain and urinary incontinence; this study explores how correcting DRA during abdominoplasty affects urinary symptoms.
  • A prospective study involved 51 post-pregnancy patients who completed questionnaires assessing urinary disorders and quality of life before and one year after surgery.
  • Results showed significant improvement in stress urinary incontinence and overall quality of life scores after surgery, suggesting that the procedure positively impacts these issues rather than worsening them.
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Investigating the growing concern of pediatric burn injuries caused by social media challenges. Adolescents, seeking fame or succumbing to peer pressure, engage in risky behaviors, recording and sharing them online. The study presents two case reports detailing severe burn injuries resulting from such challenges, highlighting the physical and psychological toll on affected children and their families.

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Breast reduction is one of the most required plastic surgery procedures worldwide, improving significantly the quality of life for patients with macromastia and gigantomachia. Despite various proposed approaches aiming to yield more stable results postreduction, no single technique has demonstrated unequivocal superiority. Recurrence ptosis at 6-12 months postoperative remains a challenging concern.

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Introduction: Grafts play key roles in functional and aesthetic rhinoplasty. Autologous grafts are generally preferred for their biocompatibility and less visibility when used in a fragmented fashion. The aim of this study was to review mechanically fragmented cartilage grafts techniques described in the literature, outlining indications, outcomes, and complications.

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Sarcoma resection often leaves patients with big defects only amenable through microsurgical reconstruction. In such cases, it is hard for the surgeon to uphold low donor-site morbidity with an aesthetic result. The purpose of this study was to investigate the clinical outcome and the patient's perception regarding the donor site in a cohort of patients undergoing microsurgical reconstruction with lateral thigh and lower abdominal perforator flaps.

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Background: Inverted-T scar reduction mammaplasty is still the most chosen technique for breast reduction even if scars are relevant. Sometimes, surgical scars may be esthetically unpleasant and may cause severe pain, tenderness, sleep disturbances, anxiety, and depression in these patients. This study aimed to assess any possible correlation between general satisfaction with the breast and appearance of the scars in patients who underwent inverted T-scar reduction mammaplasty.

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Soft tissue augmentation with fillers has witnessed a surge in popularity for rejuvenating facial features, offering solutions for wrinkles, volume loss, and contour irregularities. Non-biodegradable fillers like silicone, polyacrylamide hydrogel, and polymethylmethacrylate (PMMA) have been introduced, promising enduring results. However, reports on silicone filler usage have highlighted a spectrum of adverse events, ranging from erythema and edema to more severe complications like infection, vascular occlusion, and inflammatory nodules.

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Acne, a chronic inflammatory condition of the pilo-sebaceous unit, often results in scarring with significant aesthetic and psychological consequences for patients. While various treatments exist, including surgical and non-surgical approaches, a combined method has shown promise in effectively addressing acne scarring. Lipofilling, with its adipose-derived stem cells, has emerged as a promising technique for volume restoration and collagen stimulation but may not be suitable for all patients, especially those who prefer non-surgical treatments.

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Introduction: Eating disorders (ED) and plastic surgery are two areas of healthcare that have gained significant attention in recent years. The goal of this review is to provide an overview of the existing literature concerning the interplay between ED and aesthetic surgery, identifying existing questionnaires and providing suggestions for the future research on the psychological aspects of these group of patients.

Methods: We conducted a systematic review on PubMed.

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Liposuction is a surgical procedure used to remove localized excess adipose tissue. According to The Aesthetic Society's latest annual report, liposuction is the most commonly performed cosmetic procedure. Despite its popularity, the existing literature lacks a unified understanding of the risks associated with liposuction.

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Artificial intelligence (AI) is emerging as a promising tool in the field of plastic surgery, offering a wide array of applications that enhance surgical outcomes, patient satisfaction, and overall efficiency. This paper explores the utilization of AI, highlighting its various advantages and potential drawbacks. AI-driven technologies such as computer vision, machine learning algorithms, and robotic assistance facilitate preoperative planning, intraoperative guidance, and postoperative monitoring.

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