Publications by authors named "Perrine T"

Default Vegetarianism and Veganism.

J Agric Environ Ethics

April 2021

This paper describes a pair of dietary practices I label and . The basic idea is that one adopts a default of adhering to vegetarian and vegan diets, with periodic exceptions. While I do not exhaustively defend either of these dietary practices as morally required, I do suggest that they are more promising than other dietary practices that are normally discussed like strict veganism and vegetarianism.

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An 18-year-old female presents with acute hemoptysis and rapidly deteriorates into fulminant pulmonary and renal failure. She is ultimately diagnosed with microscopic polyangiitis with pauci- immune glomerulonephritis. This case report will delineate her presentation, work-up, broad differential diagnosis, and outcome.

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The geometric aspects for the functionality of a molecule-based field effect transistor (FET) are analyzed. A computational study is performed on molecular models involving a well-defined conjugation plane coupled to gold-based electrodes through thiol bonding. Transport gating of the FET is shown to depend on a symmetry-breaking effect induced by the gating field.

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Computational model systems are used to explore improving the transmission through a molecular device based on bridged cobalt(II) complexes. The bridging ligands and the organic conjugated molecular ligands are altered to improve the current flow through both an enhanced pi-stacking interaction as well as involving the metal ions directly in the conduction pathway. With terpyridine as the organic ligand, both acetate and NH2- produce conductive devices, while a terpyridine complex bridged by Cl- is not conductive.

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Previously we have demonstrated that several structural features are crucial for the functionality of molecular field-effect transistors. The effect of additional structural aspects of molecular wires is explored. These include the type of, the thiol binding location on, and the chemical substitutions of a conjugated system.

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A recent experiment, in which a molecular transistor based on the coordination chemistry of cobalt(II) and organic self-assembled monolayers is formed by means of self-aligned lithography,2 is analyzed with a computational approach. The calculations reveal that a complex involving two cobalt(II) ions bridged by acetate ions can effectively span the nanogap. This bridged complex is shown to be both more flexible and more conductive than the alternative structure involving a single cobalt(II) ion.

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Large increases in the conductance of peptides upon binding to metal ions have recently been reported experimentally. The mechanism of the conductance switching is examined computationally. It is suggested that oxidation of the metal ion occurs after binding to the peptide.

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Guidelines recommend that patients with persist- ent seizures not responsive to standard antiepileptic drugs after 1 year be referred to specialized epilepsy centers for evaluation, which may include inpatient video-electroencephalographic monitoring. This 1-year retrospective, limited-focus review of 213 admissions and 3-year postdischarge review of epilepsy surgery referrals sought to determine if admission to an inpatient adult epilepsy monitoring unit resulted in a definitive diagnosis, a change in diagnosis or treatment, and whether referral patterns were consistent with guidelines. The median duration of time since symptom onset prior to admission was 15 years.

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Sedimentation and diffusion constants were determined for electrophoretically purified Vi antigen before and after mild alkaline hydrolysis. The molecular weight of the intact antigen was found to be 1.7 x 10(6).

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A modification of the apparatus previously described permits the preparation of cell walls in quantity. This consists of a heavy duty, double-acting hydraulic press with motor-driven pump, and a superstrength alloy steel pressure cell which is corrosion resistant. Liquid cooling of the jet is substituted for the previously used gas cooling to minimize aerosol formation and to facilitate subsequent treatment of the products.

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