Publications by authors named "Pernille W Greisen"

Aim: Postmortem Computed Tomography (PMCT) is gradually introduced at forensic institutes. Image reconstruction software can increase diagnostic potential in CT by increasing distinction between structures and reduction of artifacts. The aim of this study was to develop and evaluate novel image reconstruction parameters for postmortem conditions, to increase image quality and diagnostic potential of CT scans.

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Article Synopsis
  • The study examines the effectiveness of ultra-low dose computed tomography (ULD-CT) in detecting acute lung conditions in Emergency Department patients, focusing on comparisons with supine chest X-ray (sCXR).
  • Accuracy and agreement among different medical staff—radiologists, senior clinicians, junior clinicians, and medical students—were evaluated using kappa statistics, with ULD-CT showing better results for detecting pneumonia and pneumothorax, especially among radiologists.
  • The findings suggest that ULD-CT could be a more reliable first-line imaging option over sCXR for non-traumatic patients in emergency settings.
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Introduction: Reducing tube voltage is an effective dose saving method in computed tomography (CT) assuming tube current is not concurrently increased. Recent innovations in scanner technology now enable CT tube voltage reduction to 70 kV thereby increasing opportunities for dose reduction in paediatric patients, but it is unclear if the increased image noise associated with 70 kV impacts on ability to visualise renal stones accurately. The purpose was to assess detectability of nephrolithiasis using a bespoke paediatric phantom and low kV, non-contrast CT and to assess inter-observer agreement.

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Article Synopsis
  • This study assessed if ultra-low-dose chest CT (ULD-CT) is better than regular chest X-rays (sCXR) for identifying acute chest issues in the emergency department.
  • Results showed ULD-CT had better sensitivity for detecting pneumonia and pneumothorax, while both methods had similar accuracy for other conditions like pleural effusion and cardiogenic pulmonary edema.
  • Although ULD-CT may be more effective, it requires more time and staff, making it less feasible in some emergency settings.
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The congenital dyserythropoietic anemias (CDAs) are a group of rare inherited blood disorders characterized by ineffective erythropoiesis as the principal cause of anemia. We present a child with CDA 1b-the rarest and least well-described type-due to a mutation in the C15orf41 gene. The patient presented with severe in utero and neonatal manifestations, typical peripheral limb anomalies as well as rarely reported cardiac manifestations, visual impairment, short stature, and hip dysplasia.

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