Interact Cardiovasc Thorac Surg
January 2020
Objectives: To assess whether sevoflurane provides better haemodynamic stability than propofol in acute right ventricular (RV) ischaemia-reperfusion.
Methods: Open-chest pigs (mean ± standard deviation, 68.8 ± 4.
Background: The intention of the present study was to evaluate possible cardioprotective properties of inhalation anesthesia with sevoflurane.
Methods And Materials: A porcine, open-chest model of right ventricular ischemia was used in 7 pigs receiving inhalation anesthesia with sevoflurane. The model was earlier developed and published by our group, using pigs receiving intravenous anesthesia with propofol.
Interact Cardiovasc Thorac Surg
January 2014
Objectives: To establish an experimental model for acute ischaemic isolated right ventricular dysfunction and the subsequent haemodynamic changes.
Methods: An open-chest porcine model with ischaemic dysfunction of the right ventricle induced by ligation of the three main branches supporting the right ventricular free wall. Invasive monitoring of mean arterial blood pressure (MAP), central venous pressure (CVP), left atrial pressure (LAP) and right ventricular pressure (RVP); ultrasonic measurement of cardiac output (CO) and calculation of haemodynamic parameters such as stroke volume (SV), systemic vascular resistance (SVR), pulmonary vascular resistance (PVR) and right ventricular stroke work (RVSW) using standard formulae.
Objective: To evaluate the long-term outcome of patients treated in the surgical intensive care unit (SICU) for abdominal sepsis.
Design: Retrospective study.
Setting: University hospital, Sweden.