Enhanced porous titanium biofunctionalization based on novel silver nanoparticles and nanohydroxyapatite chitosan coatings.

Titanium is widely used for implants however it presents limitations such as infection risk, stress shielding phenomenon, and poor osseointegration. To address these issues, a novel approach was proposed that involves fabricating porous titanium substrates, to reduce implant stiffness, minimizing stress shielding and bone resorption, and applying polymeric coatings to improve bioactivity. Composite coating prepared from chitosan, silver nanoparticles, and nanohydroxyapatite was optimized to enhance antibacterial properties and promote osseointegration.

Native Chilean Berries Preservation and In Vitro Studies of a Polyphenol Highly Antioxidant Extract from Maqui as a Potential Agent against Inflammatory Diseases.

The best conservation method for native Chilean berries has been investigated in combination with an implemented large-scale extract of maqui berry, rich in total polyphenols and anthocyanin to be tested in intestinal epithelial and immune cells. The methanolic extract was obtained from lyophilized and analyzed maqui berries using Folin-Ciocalteu to quantify the total polyphenol content, as well as 2,2-diphenyl-1-picrylhydrazyl (DPPH), ferric reducing antioxidant power (FRAP), and oxygen radical absorbance capacity (ORAC) to measure the antioxidant capacity. Determination of maqui's anthocyanins profile was performed by ultra-high-performance liquid chromatography (UHPLC-MS/MS).

Botulinum Toxin: An Effective Treatment for Flushing and Persistent Erythema in Rosacea.

Botulinum toxin has been used to treat persistent erythema and flushing in rosacea for several years. Here, we describe two women and one man, each with rosacea with flushing and permanent erythema refractory to conventional treatment, who achieved satisfactory and lasting results following intradermal application of botulinum toxin. Two different botulinum toxin types were used.

Effect of methyl jasmonate and salicylic acid on the production of metabolites in cell suspensions cultures of (Piperaceae).

Elicitation of cell suspensions culture is a strategy that could increase the production of secondary metabolites under controlled conditions. This research evaluated the effect of methyl jasmonate-MeJA and salicylic acid-SA as elicitors on the production of metabolites in cell suspensions of . The type of elicitor (MeJA or SA), the concentration of elicitor (10 μM and 100 μM), and time of exposition (3, 12, 24 h) on cell suspension were evaluated.

Linear lesions on the arm of a child: a diagnostic challenge.

There are a number of conditions that follow the lines of Blaschko. Linear discoid lupus erythematosus is a rare variant of chronic lupus erythematosus with less than 20 cases reported in children. It can be misdiagnosed as lichen striatus or linear morphea.

Health Care-Associated Infection in Solid Organ Transplant Recipients.

Background: Health care-associated infection (HAI) represent a global health problem with an increase in hospital stays, deaths, and monetary costs. Recipients of solid organ transplants are a population at risk. The objectives of the study were to characterize the incidence of HAI in renal and hepatic transplant recipients as well as to compare them with the population without transplants in intensive care units (ICU).

Excitation-emission fluorescence as a tool to assess the presence of grape-must caramel in PDO wine vinegars.

A practice in wine vinegar production is the addition of grape-must caramel to correct and unify the final colour of different batches. Although current legislation allows it, the effect in vinegars' quality has not been studied yet and it can become a fraud when it is used to simulate the effect of a longer ageing. Therefore, the aim of this work was to assess multidimensional fluorescence as a cost-effective and fast technique for detecting and quantifying grape-must caramel in vinegars.

Family Caregivers of Liver Transplant Recipients: Coping Strategies Associated With Different Levels of Post-traumatic Growth.

Objective: Analyze the influence of 2 variables (post-traumatic growth and time since liver transplantation) on coping strategies used by the transplant recipient's family members.

Methods: In all, 218 family members who were their main caregivers of liver transplant recipients were selected. They were evaluated using the Posttraumatic Growth Inventory and the Brief COPE.

How Thinking About the Donor Influences Post-traumatic Growth in Liver Transplant Recipients.

Objective: The aim of this work was to find out whether thinking frequently about the donor influences post-traumatic growth of liver transplant recipients.

Methods: The sample of 240 patients selected was made up of 185 men and 55 women with an overall mean age of 60.21 (SD 9.

Post-traumatic growth and its relationship to quality of life up to 9 years after liver transplantation: a cross-sectional study in Spain.

Objective: Little is known concerning post-traumatic growth (PTG) after liver transplantation. Against this backdrop the current study analysed the relationship between PTG and time since transplantation on quality of life. Furthermore, it compared PTG between liver transplant recipients and their caregivers.

Coping Strategies in Liver Transplant Recipients and Caregivers According to Patient Posttraumatic Growth.

The purpose of this study was to analyze the differences in coping strategies employed by liver transplant recipients and their family members according to patient posttraumatic growth. Two matched groups of 214 liver transplant recipients and 214 family members were selected. The Posttraumatic Growth Inventory and Brief COPE were used.

Cerebral Hemodynamics Patterns by Transcranial Doppler in Patients With Acute Liver Failure.

Introduction: About half of patients with acute liver failure (ALF) show clinical signs of cerebral edema and intracranial hypertension. Neuroimaging diagnostics and electroencephalography have poor correlation with intracranial pressure measurement.

Objective: The objective of this study was to characterize the cerebral hemodynamics patterns with transcranial Doppler (TCD) sonography in patients with ALF.

Comparison of the affective symptomatology between liver transplant recipients and patients with multiple sclerosis considering their functional impairment.

Objectives: We aimed to compare the affective symptomatology in two medical conditions under immunotherapy (cadaveric liver transplantation [G1] and multiple sclerosis [G2]), considering their functional impairment, and to assess the clinical significance of the results regarding a representative age-adjusted sample of the general Spanish population (G3).

Methods: Using a cross-sectional design, 164 patients (82 per clinical group) were selected, matched for gender, and homogenized regarding age and functional impairment according to the Physical functioning subscale from the SF-36 Health Survey. The criterion variables were the Mental health and Role-emotional SF-36 subscales and the Hospital Anxiety and Depression Scale.

Influence of acute cellular rejection and depressive symptomatology on liver transplant recipients' quality of life.

Background: The objective of this study was to analyze the influence of two variables (acute cellular rejection and depressive symptomatology) on liver transplant recipients' quality of life.

Methods: Using a 2 × 2 factorial design, two groups were selected: 44 patients who had acute cellular rejection and 44 patients without this medical complication. After an average of 6 years since the transplant, patients were assessed with the Hospital Anxiety and Depression Scale and the SF-36 Health Survey.

A novel approach for electromembrane extraction based on the use of silver nanometallic-decorated hollow fibers.

A novel approach based on the use of nanometallic-decorated hollow fibers to assist electromembrane extraction is proposed. Microporous polypropylene hollow fibers, on which nanometallic silver was deposited, have been used for the first time as liquid membrane support in electromembrane extraction (EME). Different methods for the generation/deposition of silver nanoparticles (AgNPs) were studied.

Evolution of anxious-depressive symptomatology in liver and kidney transplant recipients: hospitalization and 12-month post-transplantation phases.

Objective: The objective of this study was to compare the evolution (hospitalization in the transplantation unit and at 12 months post-transplantation) of anxious and depressive symptomatology in cadaveric transplant recipients as a function of type of organ implanted (liver or kidney).

Methods: Using a 2 × 2 mixed factorial design, 2 groups were selected: 34 liver transplant recipients and 41 kidney transplant recipients. Both groups were assessed in 2 phases: (1) in the transplantation unit after discharge from the intensive care unit; and (2) 12 months after discharge from the hospital following implantation surgery.

Longitudinal study of liver transplant recipients' quality of life as a function of their perception of general health: at waiting list and at 3, 6, and 12 months post-transplantation.

Objective: The objective of this study was to compare the evolution (at waiting list, and at 3, 6, and 12 months post-transplantation) of quality of life of cadaveric liver transplant recipients as a function of their perception of general health.

Methods: Two groups (15 patients with better and 15 with worse self-perception of health 1 year after transplantation) were assessed at the pretransplantation and post-transplantation phases using the EuroQol (EQ-5D) questionnaire. Mixed analysis of covariance was performed with 2 factors: phase (at waiting list and at 3, 6, and 12 months post-transplantation) and perception of general health (better and worse).

Evolution of quality of life in renal transplant recipients and patients with multiple sclerosis: a follow-up study.

Objective: We aimed to compare the evolution of quality of life in 2 medical conditions under immunotherapy (cadaveric renal transplantation [G1] and multiple sclerosis [G2]), and to assess the clinical significance of the results compared with a representative age-adjusted sample of the general Spanish population (G3).

Methods: Using a mixed design (2 × 2), the SF-36 Health Survey was administered to 60 patients with one of these clinical conditions (30 in each group; the patient group factor), matched for gender, and homogenized regarding age and working status. All renal patients had undergone transplantation 6 months before the first assessment, and all neurological patients presented a relapsing-remitting course and a mild-moderate disability level.

Affective status in liver transplant recipients as a function of self-perception of general health.

Objective: We aimed to determine whether there were differences with regard to anxiety and depressive symptomatology between liver transplant recipients with better (G(1)) versus worse (G(2)) self-perceptions of general health compared with pre-liver transplantation cirrhotic patients (G(3)).

Methods: The groups of patients included 168 recipients including 85 and 83 with better or worse self-perceptions of general health, respectively, and 75 cirrhotic pre-liver transplantation patients. For the psychological assessment we used the Hospital Anxiety and Depression Scale and the general health dimension of the SF-36 Health Questionnaire.

Biopsychosocial functioning in liver patients of alcoholic etiology as a function of self-perceived pain level.

Objective: To compare the biopsychosocial functioning among liver transplantation and cirrhotic patients as a function of self-perceived pain level.

Methods: We selected two groups of liver patients of the same gender (men) and disease etiology (alcoholic): there were 39 liver transplant recipients and 34 severe cirrhotic patients. The Hospital Anxiety and Depression Scale and the SF-36 Health Questionnaire were used.

Relatives' mental health during the liver transplantation process.

Objective: To compare the mental health of relatives of liver transplant patients during the three phases: pretransplantation, waiting list, and posttransplantation.

Materials And Methods: This follow-up study used the Hospital Anxiety and Depression Scale (HADS) to assess the relatives of 35 liver transplant patients (one relative for each patient). The anxiety-depression status was compared across the three liver transplant phases: pretransplant study (G(1)), from the first to the third month after admission to the waiting list (G(2)), and the 3 months after liver transplantation (G(3)).

Application of three phase hollow fiber based liquid phase microextraction (HF-LPME) for the simultaneous HPLC determination of phenol substituting compounds (alkyl-, chloro- and nitrophenols).

This work proposes for the first time the use of a three phase hollow fiber liquid phase microextraction (HF-LPME) procedure for the simultaneous extraction, and the later HPLC determination, of some phenol substituting compounds (alkyl-, chloro- and nitrophenols) that are considered as highly toxic compounds and/or endocrine disrupting ones. The substances studied include four chlorophenols (CPs): 2,4-dichlorophenol (2,4-DCP), 2,5-dichlorophenol (2,5-DCP), 2,6-dichlorophenol (2,6-DCP) and pentachlorophenol (PCP), three nitrophenols (NPs): 2,4-dinitrophenol (2,4-DNP), 2,5-dinitrophenol (2,5-DNP) and 2,6-dinitriphenol (2,6-DNP) and two alkylphenols (APs): tert butylphenol (TBP) and sec butylphenol (SBP). The extraction was carried out through a dihexyl ether liquid membrane supported on an Accurel(®) Q3/2 polypropylene hollow fiber.

Quality of life in spanish patients with liver transplant.

Background: Liver transplantation is the optimal method of treatment in patients with end-stage liver failure. Transplantation medicine has significantly progressed in the last time, but some psychology and psychosomatic problems still remain unsolved. Health-Related Quality of Life (HRQL) in liver transplant is considered a useful measure of evolutionary process of the illness.