Simultaneous Emergent Phenomena: Leadership and Team Synchrony.

Emergent phenomena exhibit interesting dynamics when considered individually. The present article examines two emergent processes that could be occurring simultaneously in an intense team interaction: the emergence of leaders and the emergence of autonomic synchrony within teams making dynamic decisions. In the framework of panarchy theory and related studies on complex systems, autonomic synchrony would be a fast dynamic that is shaped or controlled by leadership emergence, which is a slower dynamic.

Team Situation Awareness, Cohesion, and Autonomic Synchrony 2: Group-level Effects and their Combined Influence on Team Performance.

Situation awareness (SA) is a mental state that is instrumental to performance of complex dynamic tasks. SA within teams is thought to be supported by favorable social conditions within the team. The present study was organized in two parts: (a) causal relationships among SA, group cohesion, and autonomic synchrony, the latter being a fundamentally nonlinear process, and (b) the combined impact of the three variables on performance in a dynamic decisions task.

Team Situation Awareness, Cohesion, and Autonomic Synchrony.

Objective: This study evaluated the causal relationships among situation awareness (SA), cohesion, and autonomic synchrony () within teams. SA is often a team effort and should be more accurate in better-functioning teams.

Background: Cohesive teams perform better overall, although the relationship appears reciprocal; the relationship to SA has not been considered previously.

The Relative Influence of Drivers and Empaths on Team Synchronization.

To further the understanding of how to build or reduce synchrony in a work team, we examined two principles for defining the optimal condition to produce or limit synchrony: (a) the empath-driver ratio (relative strength of the stronger influencer compared to the receptive strength of any member in the group), and (b) the balance between autocorrelated autonomic arousal (degree to which members' signals are independent of other group members) and the degree of influence that transfers from each group member to other group members. In study 1, we employed a series of computational simulations designed to manipulate the four variables. The results indicated that there is a four-way balance between driver strength, empath strength, autocorrelational and transfer effects among team members.

A Comparison of Four Dyadic Synchronization Models.

Synchronization is a special case of self-organization in which one can observe close mimicry in behavior of the system components. Synchrony in body movements, autonomic arousal, and EEG activity among human individuals has attracted considerable attention for their possible roles in social interaction. This article is specifically concerned with autonomic synchrony and finding the best model for the dyadic relationships, with regard to both theoretical and empirical accuracy, that could be extrapolated to synchrony levels for groups and teams of three or more people.

Autonomic Synchronization, Leadership Emergence, and the Roles of Drivers and Empaths.

Synchronization of autonomic arousal levels within dyads and larger teams has been associated with several types of social-behavioral outcome. One previous study reported greater physiological influence (brain activity in one area of the parietal lobe associated with verbal activity) of leaders on followers than of followers on leaders; influence was measured pairwise within triadic problem solving groups. The present study explored synchronized autonomic arousal with leadership outcomes in two experiments with group sizes of three to eight members.

Autonomic Synchronization under Three Task Conditions and its Impact on Team Performance.

Psychologists have had a long-standing interest in the connections between group processes and team performance. The biopsychosocial perspective has piqued an interest in the connection between team processes and performance and coordinated and synchronized physiological arousal levels among team members. Studies of synchronization in work teams have been stalled by the lack of a metric that captures the total synchronization within teams of three or more people.

Physiological Synchronization and Subjective Workload in a Competitive Emergency Response Task.

Human dyads and larger teams tend to acquire synchronized movements and autonomic arousal levels while working together or simply socializing. The synchronization of arousal patterns is of theoretical interest for group dynamics because they may add predictive value to the dynamics of group cohesion and team performance. This study examined the four-way relationship among experimental conditions: team size, task difficulty, time pressure (between-subjects) and subsequent experimental sessions (within-subjects).

Autonomic Synchronization, Team Coordination, Participation, and Performance.

The synchronization of autonomic arousal levels within dyads and larger teams has become a potentially important variable in the explanation of team performance and group processes. Synchronization research with groups of three or more members has been challenging because of limited means for quantifying relationships that are more extensive than dyads. This article presents an empirical investigation of group performance and participation using a new synchronization coefficient that is grounded in nonlinear dynamical systems theory.

Turn Taking, Team Synchronization, and Non-stationarity in Physiological Time Series.

This study investigated the stationarity of electrodermal time series collected in situations where turn taking in human interactions are involved. In this context, the stationarity of the time series is the extent to which a simple model can be used to fit the entire time series. The experiment involved seven participants in an emergency response simulation against one opponent.

Physiological Synchronization in Emergency Response Teams: Subjective Workload, Drivers and Empaths.

Behavioral and physiological synchronization have important implications for work teams with regard to workload management, coordinated behavior and overall functioning. This study extended previous work on the nonlinear statistical structure of GSR series in dyads to larger teams and included subjective ratings of workload and contributions to problem solving. Eleven teams of 3 or 4 people played a series of six emergency response (ER) games against a single opponent.

Orbital decomposition for ill-behaved event sequences: transients and superordinate structures.

Time series analysis is often challenged by the presence of transient functions. We examined some types of transients found in time series of events that lend themselves to symbolic dynamics analysis through the method of orbital decomposition, which is based on the principle that chaotic series arise from coupled oscillators. Synthetic data sets were constructed to study the impact of intrusive events, intrusive series, merged functions, non-coupled oscillators, and driving oscillations on the patterns of final statistics obtained from orbital decomposition analysis.

Sentinel lymph node biopsy in patients with Stage I/II melanoma: Clinical experience and literature review.

Background: The sentinel lymph node (sN) represents one of the most powerful predictors of the outcome of patients with Stages I and II cutaneous melanoma, and may be relevant for the therapeutic planning of early-stage melanoma patients. Since adopting the technique of lymphatic mapping with vital blue dye (Patent Blue-V) in July 1993, we have periodically up-dated the methodology and revised our results in order to define the contribution of radio-guided surgery (RGS) to the detection of the sN as well as the role of intraoperative frozen section examination of the sN.

Materials And Methods: Between July 1993 and December 1997, 180 patients with clinically node-negative primary cutaneous melanoma (Stages I-II) underwent sN biopsy followed by "selective lymph node dissection" (SLND) whenever sN metastasis was detected.

Solitary fibrous tumor of the inguinal region: a clinicopathological, light-microscopic, immunohistochemical, electron microscopic and flow-cytometric DNA study.

Solitary fibrous tumors (SFTs) are rare neoplasms with a probable mesenchymal origin that were first reported in the pleura but can occur in different sites. We report a case of SFT arising in the inguinal region of a 55-year-old woman. The patient presented with a mass in the left groin; she underwent wide excision of the lesion which was well-circumscribed and without evidence of adjacent soft tissue involvement.

Malignant melanoma of soft tissues (clear cell sarcoma) of the foot. Is MRI able to perform a specific diagnosis? Report of one case and review of the radiological literature.

The magnetic resonance (MR) findings in malignant melanoma of soft tissues, also called clear cell sarcoma of tendons and aponeuroses, have been described as a focal abnormality with a specific MR pattern of increased signal intensity (relative to normal muscle) on T1 weighted sequences and variably decreased signal intensity on T2 weighted sequences (relative to surrounding fat). We have reported here a case of malignant melanoma of soft tissues of the foot, studied with ultrasonography (US) and MR, in which MR showed T1-hypointensity, T2-hyperintensity and marked gadolinium uptake. We have described the relationship between the intracytoplasmic melanin amount of and these atypical MR findings.

Preliminary analysis of a randomized clinical trial of adjuvant postoperative RT vs. postoperative RT plus 5-FU and levamisole in patients with TNM stage II-III resectable rectal cancer.

Objectives: Two-hundred eighteen patients with TNM stage II-III resectable rectal cancer, enrolled into a randomized clinical trial, were assessed for efficacy and toxicity of adjuvant postoperative radiation therapy (RT) vs. those of combined RT and chemotherapy (CT), with 5-fluorouracil (5-FU) plus levamisole. End points were overall survival, disease-free survival, the rate of loco-regional recurrence, and treatment-related toxicity.

Mapping the sentinel lymph node in malignant melanoma by blue dye, lymphoscintigraphy and intraoperative gamma probe.

Eighty-eight consecutive patients (48 men and 40 women; mean age, 58.9 years; range, 16-84 years) with clinically localized cutaneous melanoma involving the trunk, extremities or head and neck underwent lymphatic mapping at our institution. The primary melanoma had a mean thickness of 2.

Selective lymph node dissection in patients with intermediate thickness melanoma: our experience.

The role of elective lymph node dissection (ELND) for the treatment of cutaneous melanoma has been debated for many years. Actually, the value of ELND is seriously questioned because an increasing of overall survival rates has not been demonstrated. The lymphatic mapping technique, initially performed by an intradermic injection of vital blue dye, subsequently improved by the use of radioguided surgery (RGS), proved effective for the detection of clinical occult lymph node metastasis.

Adoptive immunotherapy with tumor-infiltrating lymphocytes and subcutaneous recombinant interleukin-2 plus interferon alfa-2a for melanoma patients with nonresectable distant disease: a phase I/II pilot trial. Melanoma Istituto Scientifico Tumori Group.

Background: On the basis of our previous experience, we designed this study to determine the activity and toxicity of outpatient treatment with autologous tumor-infiltrating lymphocytes (TIL) together with intermediate-dose recombinant interleukin-2 (rIL-2) and low-dose recombinant interferon alfa-2a (rIFN-alpha2a), for patients with metastatic melanoma.

Methods: Between April 1992 and October 1994, we processed 38 melanoma samples derived from 36 patients with metastases. Proliferative cultures of expanded lymphocytes (TIL) were infused only once into patients with metastatic melanoma.

Sentinel node biopsy in patients with cutaneous melanoma.

The role of elective lymph node dissection (ELND) for treatment of cutaneous melanoma is still debated. Initially, lymphatic mapping technique was performed by an intradermic injection of vital blue dye; subsequently, it was improved by the use of radioguided surgery (RGS). Preliminary experience with this technique proved effective for detection of clinical occult lymph node metastasis; it may also enable the surgeon to perform a selective lymph node dissection (SLND) to concentrate on pathologic node-positive patients for the same potential benefits that have been provided by ELND.

Radioimmunoguided surgery benefits in carcinoembryonic antigen-directed second-look surgery in the asymptomatic patient after curative resection of colorectal cancer.

Radioimmunoguided surgery (RIGS) with radiolabeled monoclonal antibodies (MoAbs) has been reported as useful in second-look colorectal cancer procedures to improve surgical decision-making by helping avoid needless extensive surgery and expanding curative resection to sites of recurrence that have been missed previously. Sixteen asymptomatic patients with an history of colorectal cancer surgery underwent second-look surgery using the RIGS system, solely on the basis of rising serum levels of carcinoembryonic antigen (CEA). All patients were injected preoperatively with the anti-tumor-associated glycoprotein (TAG) 125I-labeled MoAb B72.

Role of tumor-associated antigen expression in radioimmunoguided surgery for colorectal and breast cancer.

One hundred thirty-six patients with colorectal and breast cancer were enrolled in a retrospective study using radioimmunoguided surgery (RIGS) with Iodine-125 (I125) radiolabeled B72.3 (Group A, 73 patients) and F023C5 (Group B, 63 patients) monoclonal antibodies (MAbs). The correlation between intraoperative tumor-to-normal tissue (T/NT) gamma-detecting probe (GDP) counts ratio and the expression of tumor-associated glycoprotein (TAG)-72 (GroupA patients) and carcinoembryonic antigen (CEA; Group B patients) tumor-associated antigens (TAA) expression of 209 resected or biopsy tumor specimens was assessed.

Pseudomixoma peritonei: a case report.

Pseudomixoma peritonei is a rare neoplasm characterized by mucinous ascites and the mucinous involvement of peritoneal surfaces, omentum and bowel loops. Usually pseudomixoma peritonei is associated with benign or malignant mucinous tumor of the appendix or ovary. The diagnosis of pseudomixoma peritonei is difficult because laboratory and radiology results are frequently nondiagnostic.

Merkel cell carcinoma of the skin. Treatment of primary, recurrent and metastatic disease: review of clinical cases.

The clinical features of 10 cases of primary neuroendocrine carcinoma of the skin (Merker cell tumor) are reported. This cancer arises in the dermis and subcutaneous tissues of elderly individuals. Natural history is characterized by local recurrences (30%), regional lymph node metastases (65%) and distant metastases (40%).