A Systematic Review on the Advancements in Remote Sensing and Proximity Tools for Grapevine Disease Detection.

Grapevines ( L.) are one of the most economically relevant crops worldwide, yet they are highly vulnerable to various diseases, causing substantial economic losses for winegrowers. This systematic review evaluates the application of remote sensing and proximal tools for vineyard disease detection, addressing current capabilities, gaps, and future directions in sensor-based field monitoring of grapevine diseases.

Comparative Analysis of TLS and UAV Sensors for Estimation of Grapevine Geometric Parameters.

Understanding geometric and biophysical characteristics is essential for determining grapevine vigor and improving input management and automation in viticulture. This study compares point cloud data obtained from a Terrestrial Laser Scanner (TLS) and various UAV sensors including multispectral, panchromatic, Thermal Infrared (TIR), RGB, and LiDAR data, to estimate geometric parameters of grapevines. Descriptive statistics, linear correlations, significance using the F-test of overall significance, and box plots were used for analysis.

Screening and early detection of post-extubation oropharyngeal dysphagia: a best practice implementation project.

Introduction: Patients undergoing intubation and mechanical ventilation in an intensive care unit risk developing post-extubation oropharyngeal dysphagia (PED). PED can lead to aspiration complications, aspiration pneumonia, and prolonged hospitalization, as well as increased repeat intubation and in-hospital morbidity and mortality.

Objective: This evidence implementation project aimed to promote evidence-based screening and early detection of PED in an adult intensive care unit in a secondary public hospital in Brazil.

Ciprofloxacin versus levofloxacin prophylaxis in hematopoietic stem cell transplantation: A randomized trial.

Objectives: We aimed to assess whether there is a difference between ciprofloxacin and levofloxacin as prophylaxis in hematopoietic stem cell transplant (SCT) recipients.

Methods: This is a prospective, randomized trial in patients receiving SCT at Henry Ford Health in the United States of America. We randomly assigned patients (1:1) to receive ciprofloxacin or levofloxacin.

The Development of a One-Step RT-qPCR for the Detection and Quantification of Viable Forms of in Açai Samples from Areas at Risk of Chagas Disease through Oral Transmission.

Currently, approximately 70% of new cases of Chagas disease (CD) in Brazil are attributed to oral transmission, particularly through foods such as açaí, bacaba, and sugarcane juice, primarily in the northern and northeastern regions of the country. This underscores the imperative need to control the spread of the disease. The methods utilized to conduct quality control for food associated with outbreaks and to assess the potential for the oral transmission of CD through consuming açaí primarily rely on isolating the parasite or inoculating food into experimental animals, restricting the analyses to major research centers.

Pleonotoquinones, Cytotoxic Oxepinenaphthoquinones from .

Two unusual naphthoquinones, named here as pleonotoquinones A () and B (), were isolated along with two known anthraquinones ( and ) via chromatographic separations of an ethyl acetate extract of the roots of . Compounds and are the first examples of quinones bearing a 2-methyloxepine moiety. The compounds were isolated with the aid of mass spectrometry and molecular networking, and their structures were resolved using 1D and 2D NMR and HRESIMS data.

Empowering Deaf-Hearing Communication: Exploring Synergies between Predictive and Generative AI-Based Strategies towards () Sign Language Interpretation.

Communication between Deaf and hearing individuals remains a persistent challenge requiring attention to foster inclusivity. Despite notable efforts in the development of digital solutions for sign language recognition (SLR), several issues persist, such as cross-platform interoperability and strategies for tokenizing signs to enable continuous conversations and coherent sentence construction. To address such issues, this paper proposes a non-invasive Portuguese Sign Language ( or LGP) interpretation system-as-a-service, leveraging skeletal posture sequence inference powered by long-short term memory (LSTM) architectures.

Physical Activity Attenuates Brain Irradiation-Associated Skeletal Muscle Damage in the Rat.

Purpose: Radiation therapy for brain tumors increases patient survival. Nonetheless, side effects are increasingly reported such as cognitive deficits and fatigue. The etiology of fatigue remains poorly described.

Discovering New Natural Products Using Metabolomics-Based Approaches.

The incessant search for new natural molecules with biological activities has forced researchers in the field of chemistry of natural products to seek different approaches for their prospection studies. In particular, researchers around the world are turning to approaches in metabolomics to avoid high rates of re-isolation of certain compounds, something recurrent in this branch of science. Thanks to the development of new technologies in the analytical instrumentation of spectroscopic and spectrometric techniques, as well as the advance in the computational processing modes of the results, metabolomics has been gaining more and more space in studies that involve the prospection of natural products.

Fully automated sequential immunofluorescence (seqIF) for hyperplex spatial proteomics.

Tissues are complex environments where different cell types are in constant interaction with each other and with non-cellular components. Preserving the spatial context during proteomics analyses of tissue samples has become an important objective for different applications, one of the most important being the investigation of the tumor microenvironment. Here, we describe a multiplexed protein biomarker detection method on the COMET instrument, coined sequential ImmunoFluorescence (seqIF).

Applicability of the Milan system for reporting salivary gland cytopathology: A single Brazilian institution experience.

Introduction: The Milan System for Reporting Salivary Gland Cytopathology (MSRSGC) emerged in 2015 as an attempt to establish protocols for a most appropriate follow-up and treatment of patients with salivary gland lesions. Through fine needle aspiration (FNA), a safe and minimally invasive way to obtain cytological samples, the lesion is classified into one of the six categories, which have different risks of malignancy (ROM) and, therefore, different management.

Materials And Methods: FNA cytology procedures performed between January 2016 and June 2020 (54 months) at the Pathology Institute of Araçatuba, São Paulo, Brazil, were analyzed by two pathologists with more than 5 years of experience.

Discovery of dual PKS involved in sclerotiorin biosynthesis in Penicillium meliponae using genome mining and gene knockout.

Fungi of the genus Penicillium section Sclerotiora have as their main characteristic the presence of orange-pigmented mycelium, which is associated with sclerotiorin, a chlorinated secondary metabolite of the azaphilone subclass of polyketides. Sclerotiorin presents anti-diabetes, antioxidant, anti-inflammatory, anti-Alzheimer, antiviral, and antimicrobial activities, which has always attracted the attention of researchers worldwide. During our ongoing search for azaphilone-producing Amazonian fungi, the strain of Penicillium MMSRG-058 was isolated as an endophyte from the roots of Duguetia stelechantha and showed great capacity for producing sclerotiorin-like metabolites.

UAV-Based Hyperspectral Monitoring Using Push-Broom and Snapshot Sensors: A Multisite Assessment for Precision Viticulture Applications.

Hyperspectral aerial imagery is becoming increasingly available due to both technology evolution and a somewhat affordable price tag. However, selecting a proper UAV + hyperspectral sensor combo to use in specific contexts is still challenging and lacks proper documental support. While selecting an UAV is more straightforward as it mostly relates with sensor compatibility, autonomy, reliability and cost, a hyperspectral sensor has much more to be considered.

Simvastatin protects against intestinal ischemia/reperfusion-induced pulmonary artery dysfunction.

Aims: The lung is an important target organ damage in intestinal ischemia/reperfusion (II/R), but mechanisms involved in II/R-induced pulmonary artery (PA) dysfunction, as well as its treatment, are not clear. The present study aimed to investigate the mechanisms involved in the II/R-induced PA dysfunction and a possible protective role of acute simvastatin pretreatment.

Main Methods: Male Wistar rats were subjected to occlusion of the superior mesenteric artery for 45 min followed by 2 h reperfusion (II/R) or sham-operated surgery (sham).

Ascomycota as a source of natural colorants.

In the last few decades, there has been a great demand for natural colorants. Synthetic colorants are known to be easy to produce, are less expensive, and remain stable when subjected to chemical and physical factors. In addition, only small amounts are required to color any material, and unwanted flavors and aromas are not incorporated into the product.

Critical Stepwise Decline of Antibodies against SARS-CoV-2 among Chronic Hemodialysis Patients 180 Days Post Comirnaty Vaccine.

Background: The reduced immune response of maintenance hemodialysis patients to coronavirus disease 2019 (COVID-19) vaccines is a major concern.

Objectives: To analyze the late (6 months after full vaccination) antibody response and compare it to early post-vaccination titer.

Methods: We conducted a multicenter prospective study of 13 hemodialysis units in Israel.

Adsorption kinetics and equilibrium of Ni, Cu, Co, and Ag on geopolymers derived from ashes: application to treat effluents from the E-Coat printing process.

Geopolymers were obtained from ashes through an alternative geopolymerization process and applied to remove Ni, Cu, Co, and Ag from synthetic aqueous media and real effluents. The study in synthetic solutions revealed that pseudo-second-order and general order models were the best to fit the kinetic curves. To represent the equilibrium curves, Langmuir and Freundlich were the most adequate.

Cardiovascular toxicity following immune checkpoint inhibitors: A systematic review and meta-analysis.

Background: Immune checkpoint inhibitors may be associated with multiple immune-related toxicities. Cardiovascular adverse effects are underreported in clinical trials.

Methods: We conducted a systematic review and meta-analysis to evaluate cardiovascular adverse effects incidence among patients with solid tumors receiving immune checkpoint inhibitors in randomized clinical trials and the relative risk of presenting these effects compared to placebo or best supportive care.