[Related to age and length of service, changes in psycho-physiologic occupationally important traits of technologic processes operators].

Psycho-physiologic occupational fitness of technologic processes operators changes during long-standing work in the occupation. The changes are age-related. Over 50 years of age, attention and mental performance do not satisfy the level required, so occupational fitness should be re-assessed after 50 years of age.

[Content of trace elements in the bottoms of open water reservoirs in the Western part of the Orenburg Region].

The mean concentrations of trace elements were determined in the bottoms of open water reservoirs in the western part of the Orenburg Region. The content of chromium was found to exceed the maximum permissible concentration by about 5 times, that of zinc and nickel complies with the clarke; that of copper was nearly 2 times less than the clarke, that of cobalt and vanadium is nearly 1.5 times less.

[Changes in the indices of lipid metabolism in patients with ischemic heart disease occupied in natural gas fields].

The influence of adaptation to periodic pressure-chamber hypoxia produced on the condition of the lipid spectrum of blood serum before and after adaptation as well as in 3, 6 and 10 months after hypoxic training was studied in 46 patients with ischemic heart disease working at a enterprise specializing in winning and processing the hydrogen-sulfide-containing gas-condensate. The adaptation therapy was found to result in a reliable reduction of the total cholesterol level, of the level of cholesterol of lipoproteins of the low and extra low densities and of triglycerides; it also contributed to the increase of cholesterol of lipoproteins of the high density in blood serum, which, in the end, ensures a reduced atherogenic coefficient. The positive-for-organism changes in the lipid spectrum of blood serum hold on in patients with coronary heart disease for as long as 6 months after the adaptation therapy.

[Hygienic estimation of the levels of chemical substances in the soil of the Orengurg region].

Soil pollution has been comprehensively assessed in the agroindustrial region and its sources were defined. The results of ecological and hygienic assessment of natural and anthropogenic soil pollution suggest that there are increased concentrations of boron, chromium, nickel, and lead and deficient levels of iodine throughout the territory. There are higher levels of metal accumulation in the soil of the Eastern area.

[Hygienic assessment of physical and psychophysiologic development of children residing in the area of emissions of Orenburg gas-producing plants].

The children and adolescents residing in rural settlements located in the vicinity of sites of industrial extraction and processing of hydrogen sulphide-containing gas were studied. The drinking water and ambient air in these settlements were shown to be polluted. Low indices of the children's mental, physiological, and physical development were revealed.

[Hygienic aspects of air pollution by sulfur-containing compounds].

The physiological and biochemical states of children and adults who resided in the vicinity of the sulphide-containing gas processing plant were studied. The chemical agents emitted by the plant were found to have adverse effects of the children's functional status, namely, decreased vital capacity of the lung, mental performance, retarded sensomotor responses, altered enzymatic system activity.

[Effects of hydrogen sulfide containing gas condensate on the hepatic microsomal monooxygenase system].

Chronic action of different xenobiotics which form a part of condensed hydrogen sulphide-containing gas causes substantial changes in the activity of xenobiotic metabolic enzymes, which is suggestive of the damaged hepatic microsomal monooxygenase system. As the rate of biotransformation becomes higher, there are increases in the activity of microsomal monooxygenases and in the generation of active oxygen forms and hydrogen peroxide, by impairing antiradical and antiperoxide mechanisms. The experimentally used concentration of substances as constituents of condensed gas corresponds to the maximum acceptable air concentration of in the working area of gas-refining plants, but the functional features of the body's detoxifying system--the hepatic monooxygenase system should be taken into account while developing preventive measures of occupational diseases.

[The characteristics of the behavior and brain lipid peroxidation function of rats in acute inhalation exposure to a hydrogen sulfide-containing gas condensate].

As a result of the effect of the gas condensate containing hydrogen sulfide a depression takes place of orienting-investigatory activity of Wistar male rats in conditions of open field, disturbance of elaboration and reproduction of conditioned reflex of two-way avoidance, surplus accumulation in the cerebral cortex tissue of products of peroxide lipids oxidation and depression of catalase. The changes were of cyclic character and returned to the level of the control animals in 48 h after the finishing of the effect.