Publications by authors named "Pereira G"

Objective: To assess the usefulness of night-time presentations to measure alcohol-related harm (ARH) in young trauma patients, aged 12-24 years, attending Western Australian EDs.

Methods: A retrospective longitudinal study examined alcohol-related ED presentations in Western Australia (WA; 2002-2016) among 12- to 24-year-olds. Data from the Emergency Department Data Collection, WA State Trauma Registry Database and Hospital Morbidity Data Collection were used to identify ARH through specific codes and text searches.

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Foodborne diseases are a major challenge in the global food industry, especially those caused by multidrug-resistant (MDR) bacteria. Bacteria capable of biofilm formation, in addition to MDR strains, reduce the treatment efficacy, posing a significant threat to bacterial control. Bacteriophages, which are viruses that infect and kill bacteria, are considered a promising alternative in combating MDR bacteria, both in human medicine and animal production.

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The LUX-ZEPLIN experiment is a dark matter detector centered on a dual-phase xenon time projection chamber operating at the Sanford Underground Research Facility in Lead, South Dakota, USA. This Letter reports results from LUX-ZEPLIN's first search for weakly interacting massive particles (WIMPs) with an exposure of 60 live days using a fiducial mass of 5.5 t.

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Different studies have suggested that fluoride can induce apoptosis in non-skeletal tissues, however, evidence from these experimental studies is still controversial. This meta-analysis aims to clarify the mechanism of fluoride-induced apoptosis in non-skeletal tissues of experimental animals. Primary studies which measured apoptosis were identified through exhaustive database searching in PubMed, Embase, Web of Science Core Collection, Scopus, and references of included studies.

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  • Coarse-grained (CG) modelling using the Martini force field has advanced significantly, allowing accurate simulations of large biomolecular structures over millisecond timescales.
  • The updated Martini 3 model has potential applications in drug discovery, particularly in drug design and delivery, due to its efficiency and ability to explore a wide range of chemical scenarios.
  • However, improvements are needed in areas like automatic parameterization, protein flexibility representation, and better sampling methods before it can be widely adopted in research and industry.
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  • The study investigates how gestational diabetes mellitus (GDM) affects early childhood developmental vulnerabilities in children, particularly focusing on direct and indirect impacts through preterm birth.
  • Data from multiple databases in Western Australia was analyzed, revealing that 22% of children were developmentally vulnerable in at least one domain, and 11% in two domains, with GDM significantly increasing these risks.
  • Findings suggest that while GDM exposure is linked to higher developmental vulnerability, only a small portion of this effect is explained by preterm births, indicating other biological mechanisms might be at play.
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Pasture-based dairy herds continue to grow around the world as demand increases for sustainable farming practices. Grazing dairy farmers may benefit from the utilization of precision dairy technologies because these technologies have the potential to improve animal welfare, increase farm efficiency, and reduce costs. Precision dairy technologies have provided novel information about activity, rumination, and grazing behavior of various breeds in pasture-based systems.

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Statement Of Problem: The color of monolithic zirconia restorations is obtained by presintering or postsintering coloring techniques. However, studies on the differences in surface characteristics and their influence on color stability are lacking.

Purpose: The purpose of this in vitro study was to evaluate the influence of shading and staining techniques for a zirconia ceramic on the surface characteristics and colorimetric parameters (color difference, translucency, and whiteness index) after exposure to coffee or red wine and then polishing.

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The inappropriate use of antimicrobials, along with environmental conditions, can lead to the emergence of resistant microorganisms. The use of phytopharmaceuticals and herbal medicines has a positive impact and represents a promising alternative. extracts have been widely reported to have antimicrobial potential; however, studies reporting their activity against resistant bacterial strains are scarce.

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Objective: To evaluate the effects of cusp inclination of the prosthetic preparation's occlusal surface and type of restorative material on the fatigue behavior, failure mode, and stress distribution of occlusal veneers.

Materials And Methods: Glass fiber-reinforced epoxy resin prosthetic preparations for occlusal veneers with three different occlusal surface cusp inclination degrees (0°, 15°, and 30°) were produced and assigned into six testing groups (n = 11) according to the cusp inclination (0°, 15°, or 30°) and type of restorative material (lithium disilicate-LD or resin composite-RC). Despite different substrate preparation cusp inclination degrees, the restorations were designed maintaining 30° inclination between the cusps at the occlusal surface and a thickness of 0.

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  • The Chikungunya virus poses a significant public health threat in the Americas, with over 120,000 cases and 51 fatalities reported in 2023.
  • Paraguay was the most affected, accounting for 46 of those deaths.
  • Researchers used advanced genomic, phylodynamic, and epidemiologic methods to study and understand the current chikungunya epidemic in Paraguay.
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Hypothyroidism is an endocrine-metabolic disorder, and as such it compromises a wide range of physiological functions. Memory deficits and, the most recently described, circadian rhythm disruption are among the impairments caused by thyroid dysfunctions. However, although highly likely, there is no evidence connecting these two effects of hypothyroidism.

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  • * Collaborative efforts led to the collection of 422 chikungunya virus genomes from 12 states, offering insights into how the virus has spread and evolved across the country.
  • * Analysis of the genetic data revealed two distinct subclades of the virus and highlighted Northeast Brazil as the main spreading region, with immune system factors potentially influencing its genetic diversity.
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This study aimed to evaluate the effect of different concentrations of sodium hypochlorite (NaOCl) and calcium hypochlorite [Ca(OCl)2] on the bond strength and adaptation of glass fiber posts luted with a dual-curing resin cement. Fifty decoronated premolars were sectioned 14 mm from the apex and endodontically treated. The root canal filling was partially removed.

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The human gut microbiota is able to degrade otherwise undigestible polysaccharides, largely through the activity of the . Uptake of polysaccharides into is controlled by TonB-dependent transporters (TBDT) whose transport is energized by an inner membrane complex composed of the proteins TonB, ExbB, and ExbD. encodes 11 TonB homologs which are predicted to be able to contact TBDTs to facilitate transport.

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The increasing intake of ultra-processed (UP) foods is causing changes in the profile of food and nutrient consumption, negatively influencing consumer behavior. The present study aimed to evaluate the influence of UP foods on the diet of Brazilian adults, verifying the association between its increasing contribution to total energy and trends in the consumption of other NOVA groups, food subgroups, energy consumption, and macro- and micronutrients. We conducted an observational, cross-sectional study of a probability sample of 921 manufacturing workers in the state of Rio Grande do Norte, Brazil, from a combined stratified and two-stage survey.

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The complete characterization of wood, with the determination of the 12 elastic constants that represent its orthotropy, is greatly relevant in applications employing structural calculation software programs. Ultrasound allows for such characterization with relative simplicity when compared to other methods. The polyhedron is considered the most appropriate specimen format for allowing the 12 constants to be calculated with a single specimen, and the traditionally used one is the 26-sided polyhedron, which, to be produced manually with more precision in directing the main directions of the wood, needs larger faces.

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Chikungunya (CHIK) is a debilitating mosquito-borne disease with an epidemiology and early clinical symptoms similar to those of other arboviruses-triggered diseases such as dengue or Zika. Accurate and rapid diagnosis of CHIK virus (CHIKV) infection is therefore challenging. This international study evaluated the performance of the automated VIDAS anti-CHIKV IgM and IgG assays compared to that of manual competitor IgM and IgG ELISA for the detection of anti-CHIKV IgM and IgG antibodies in 660 patients with suspected CHIKV infection.

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Background: Several HCV patients in Brazil were lost to follow-up (LTFU) in the last two decades before achievement of sustained virological response (SVR). Strategies to recall those diagnosed but untreated patients have been used elsewhere with different success rates.

Aim: To identify and retrieve LTFU patients in order to offer them the treatment with the current highly effective direct acting antiviral agents (DAAs).

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Background/objectives: Bacterial infections (BIs) are well-recognized precipitants of hepatic encephalopathy (HE). Nevertheless, there is a paucity of data in patients with HE associated with BI. Our aim was to describe clinical characteristics, recurrence, and prognosis of HE in patients with BI.

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Tambaqui (Colossoma macropomum) is a species of great cultural and economic importance in aquaculture in the Amazon region. Methionine is considered the first limiting sulfur amino acid in practical fish diets, which encourages investigating its use in diets for tambaqui. This study aimed to verify the digestible methionine plus cystine (Met + Cys) requirement in diets for tambaqui (89.

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Article Synopsis
  • Immunotherapy is the primary treatment for advanced non-small cell lung cancer (NSCLC), but effective predictive biomarkers of clinical response are limited, highlighting the need for better real-time monitoring methods.
  • Liquid biopsies measuring circulating tumor DNA (ctDNA) and immune response dynamics were used in a study of metastatic NSCLC patients undergoing immunotherapy, finding that molecular response was closely linked to survival outcomes.
  • The study concluded that tracking molecular responses through minimally invasive techniques can enhance understanding of treatment effects, particularly in patients with stable disease and those experiencing immune-related adverse events.
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Whipple's disease (WD) is caused by , frequently found in lamina propria's macrophages in the small intestine. It is a rare and chronic systemic infection, and the principal clinical manifestations are diarrhea, weight loss, abdominal pain, and arthralgia. The diagnosis is difficult mainly because of its rarity and should be considered in patients with arthralgias, diarrhea, abdominal pain, and weight loss after more common conditions have been excluded.

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Background: High-dose chemotherapy followed by hematopoietic stem cell transplantation (HSCT) is associated with a high symptom burden including sleep disturbance. Here we present the results of a secondary analysis of a randomized, sham-controlled trial assessing the effect of acupuncture on sleep quality during HSCT.

Methods: Adult multiple myeloma patients undergoing inpatient and outpatient autologous HSCT were randomized and blinded to receive either true or sham acupuncture (by licensed acupuncturists) once daily for 5 days starting the day after chemotherapy.

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