Is it possible to refine the indication for sentinel node biopsy in high-risk ductal carcinoma in situ?

Background: The indication for sentinel node biopsy (SNB) has not been fully established yet for patients with ductal carcinoma in situ (DCIS).

Aim: To relate the conversion rate to invasive carcinoma with sentinel node positivity in high risk DCIS, and to refine the clinical presentation analysis in order to better select patients for SNB. For this purpose, a risk score was devised.

[Radio-guided occult lesion localization combined with sentinel node biopsy in women with breast cancer].

Introduction: The practice of intratumoral radiocolloid injection for sentinel node biopsy (SNB) allows localization of nonpalpable breast tumors in the same surgical intervention, using the technique known as radio-guided occult lesion localization (ROLL).

Patients And Method: We present our experience with the combined use of both techniques (SNB and ROLL). A total of 233 patients were retrospectively analyzed: 65 patients underwent ROLL and 168 patients underwent wire-guided localization (control group) as the excision modality.

Nifedipine versus ritodrine for suppression of preterm labor. Comparison of their efficacy and secondary effects.

Objectives: To compare the efficacy of nifedipine and ritodrine in prolonging pregnancy beyond 48 h, 1 week and 36.0 weeks and to evaluate maternal side effects and adverse perinatal outcome.

Study Design: Non-blinded, randomized controlled trial.