[Assessment of the health-related quality of life impact in female with mixed urinary incontinence].

Background: Health-related quality of life (HRQoL) assessment on female with urinary incontinence (UI) may be a useful indicator in the management of early treatment depending on the sort of UI which is dominant: Stress UI or Urge UI. The objective of the present study was to evaluate the HRQoL of female with mixed UI, comparing the impact of symptoms of Urge UI and Stress UI.

Patients And Methods: This is an epidemiologic, cross-sectional and multicenter study.

Cizolirtine citrate, an effective treatment for symptomatic patients with urinary incontinence secondary to overactive bladder: a pilot dose-finding study.

Background: A dose-finding study was performed as the first step in the clinical development of the new drug, cizolirtine citrate.

Objective: To assess the efficacy and safety of cizolirtine citrate in overactive bladder with urinary incontinence.

Design, Setting, And Participants: Seventy-nine outpatients with clinical overactive bladder and/or urodynamic diagnosis of detrusor overactivity were randomized in a multicentre, 12-wk, double-blind, pilot trial.